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Hypertension and Diabetes Mellitus

Gurushankar Govindarajan, James R Sowers, Craig S Stump,

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The Science of Ultrasound Renal Denervation

Philipp Lurz, Michael Joner, Felix Mahfoud et al

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Syncope in the Elderly

Helen O’Brien, Rose Anne Kenny,

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Home Blood Pressure Monitoring

Jacob George, Thomas M MacDonald,

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Clinical Diagnosis and Management of Resistant Hypertension

Costas P Tsioufis, Alexandros Kasiakogias, Dimitris Tousoulis,

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Baroreflex Sensitivity Assessment - Latest Advances and Strategies

Maria Teresa La Rovere, Roberto Maestri, Gian Domenico Pinna,

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Hypertension and Stroke: Update on Treatment

Mauricio Wajngarten, Gisele Sampaio Silva,


Hypertension is the most common modifiable risk factor for cardiovascular disease and death, and lowering blood pressure with antihypertensive drugs reduces target organ damage and prevents cardiovascular disease outcomes.

Most hypertensive patients will need a combination of antihypertensive agents to achieve the therapeutic goals. Recent guidelines recommend initiating treatment with two drugs in those patients with a systolic blood pressure >20 mmHg and/or a diastolic blood pressure >10 mmHg above the goals, and in those patients with high cardiovascular risk. In addition, approximately 25% of patients will require three antihypertensive agents to achieve the therapeutic targets.

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