Coronary Physiology

About

Invasive coronary physiology is a key instrument in decision making for the interventional cardiologist.

Fractional flow reserve (FFR) has been well validated in chronic stable coronary artery disease. FFR is the ratio of the pressure distal to a lesion relative to the aorta pressure during maximal hyperaemia. Its practical applications are expanding into other clinical situations, including acute coronary syndrome, severe aortic stenosis and post percutaneous coronary intervention.

Instant wave-free ratio (iFR) is a resting index used to assess severity of an intracoronary stenosis. It measures the ratio of mean coronary pressure distal to a stenosis to the mean aortic pressure during an isolated period of diastole – the “wave-free period”.

It is an attractive alternative to FFR because it does not require hyperaemia, and therefore has a lower incidence of patient discomfort, side-effects, and shorter procedural time.

Articles

Management of Coronary Disease in TAVI Patients

Published:

07 December 2021

Citation:

European Cardiology Review 2021;16:e49.

Comments on TARGET FFR and DEFINE-FLOW Trials Presented at TCT Connect 2020

Published:

27 April 2021

Citation:

European Cardiology Review 2021;16:e17.

Editorial: The EXCEL Trial

Published:

30 March 2021

Citation:

European Cardiology Review 2021;16:e09.

Latest Advances in Cardiac CT

Published:

26 February 2020

Citation:

European Cardiology Review 2020;15:e01.