ESC 23: Hot Line & Late-breaking Science Video Collection

  • Published:  04 August 2023
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ESC 23: Hot Line & Late-breaking Science Video Collection

  • Published:  04 August 2023
  • Views: 

    Views Icon

    5466

  • Likes: 

    Heart Icon

    3

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About the episode

ESC 2023 — Prof Julian Gillmore (University College London, UK) joins us onsite to discuss the findings of the ATTRibute-CM Study. 

ATTRibute-CM was a randomised double-blind trial which aimed to evaluate the safety and efficacy of acoramidis in a cohort of patients diagnosed with transtherytin amyloid cardiomyopathy (ATTR-CM). 632 patients were enrolled in the trial, and were randomised 2:1 to receive either oral acoramidis 800mg twice daily, or placebo for 30 months. Patients had the option tafmidis after 12 months. 

Results showed that acoramidis improved outcomes in patients with ATTR-CM when compared to placebo, with an absolute risk reduction of 6.4%, relative risk reduction of 25%, and a hazard ratio of 0.772.

Recorded on-site at ESC Congress 2023, Amsterdam.

Editors: Mirjam Boros and Jordan Rance
Video Specialists: Dan Brent, Tom Green, Mike Knight, Oliver Miles

Overview

What's hot at the European Society of Cardiology (ESC) Congress 2023?

Browse our curated coverage of the latest updates in cardiology from Amsterdam.

  • Watch our View From the Thoraxcenter series for a concise line up of the most awaited trials from Prof Nicolas Van Mieghem and Dr Joost Daemen
  • For a deeper dive into key clinical trial data and its applicability, host, Dr Harriette Van Spall meets with Principal Investigators in her Late-Breaker Discussion series.
  • View a condensed summary of the crucial takeaways from each day in our Wrap-Up series with Dr Mirvat Alasnag.
  • Our short, accessible Expert Interviews with select faculty focus on data, patient care and the future of their field.
  • We will feature personal perspective in Behind the Heart series focusing on career pathways, personal motivations and perspectives on the field.

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Part 4

Expert Interviews

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Part 6

Behind the Heart

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Faculty Biographies

Julian Gillmore

Julian Gillmore

Julian Gillmore gained his medical degree at University of London. He trained in nephrology and undertook MD and PhD degrees in the field of amyloidosis. His research interests include pathogenesis, diagnosis and treatment of amyloidosis.

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