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Coronary Artery Spasm: The Interplay Between Endothelial Dysfunction and Vascular Smooth Muscle Cell Hyperreactivity
Author(s): Astrid Hubert , Andreas Seitz , Valeria Martínez Pereyra , et al Added: 3 years ago
Coronary artery spasm (CAS) is an established cause for anginal chest pain, the cardinal symptom of myocardial ischaemia, in patients with angiographically unobstructed coronary arteries. Evidence from large clinical studies has revealed that about 50% of patients undergoing diagnostic coronary angiography for suspected coronary artery disease (CAD) had either normal or near normal coronary… View more

Prevention & Chronic Conditions
Author(s): Roos ET van der Meer , Angela Maas Added: 2 years ago

Vascular Disease and Surgery
Invasive Diagnosis of Coronary Functional Disorders Causing Angina Pectoris
Author(s): Sascha Beck , Valeria Martínez Pereyra , Andreas Seitz , et al Added: 2 years ago

Prevention & Chronic Conditions
Mechanisms of Coronary Artery Spasm
Author(s): Kensuke Nishimiya , Jun Takahashi , Kazuma Oyama , et al Added: 10 months ago

Prevention & Chronic Conditions
Author(s): Juan Carlos Kaski , Hiroaki Shimokawa Added: 7 months ago

Vascular Disease and Surgery

Prevention & Chronic Conditions
The Effect of Statins on the Functionality
Author(s): Nilofer Sorathia , Hussein Al-Rubaye , Benham Zal Added: 3 years ago
Statins are most frequently prescribed for the primary prevention of cardiovascular disease due to their lipid-lowering properties. They are known to exert their effect by competitive inhibition of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase. The reduction in the synthesis of cholesterol induces upregulation of LDL receptors in the liver, resulting in increased clearance and… View more

Anticoagulation

Prevention & Chronic Conditions
Management of Coronary Artery Spasm
Author(s): Gaetano Antonio Lanza , Hiroaki Shimokawa Added: 11 months ago

Vascular Disease and Surgery

Prevention & Chronic Conditions
Author(s): Daniel Alejandro Lerman , Nasri Alotti , Kiddy Levente Ume , et al Added: 3 years ago
Acute myocardial infarction (AMI) is still a major public health problem worldwide, causing high rates of morbidity and mortality. In the United States, nearly one million patients suffer from AMI each year.1 In the UK, around 80,000 people died from coronary heart disease (CHD) in 2010.2 The current approach to the treatment of myocardial infarction involves early revascularisation with… View more

Vascular Disease and Surgery

Heart Failure
Author(s): Gustav Steinhoff Added: 3 years ago
Cell therapy for myocardial regeneration is an exciting new field of medical research that has the potential to revolutionise cardiovascular medicine. Despite significant improvements in emergency treatment, myocardial infarction (MI) leads to a net loss of contractile tissue in many patients with coronary artery disease (CAD). Often, this is the beginning of a downward spiral towards congestive… View more

Vascular Disease and Surgery

MI/ACS