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Author(s):
Markus P Schlaich
Added:
1 year ago
AHA 2022 — Dr Markus P Schlaich (University of Western Australia, AU) joins us to discuss the key findings from the PRECISION trial (NCT03541174).This randomized, phase 3 study assessed the sustained blood pressure lowering effect of a dual endothelin receptor antagonist, aprocitentan (Idorsia Pharmaceuticals Ltd.) in resistant hypertension.
Presented first at AHA 22, the trial showed that…
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Author(s):
Costas P Tsioufis
,
Alexandros Kasiakogias
,
Dimitris Tousoulis
Added:
3 years ago
Recent guidelines have defined resistant hypertension (RHT) as blood pressure (BP) that does not fall below 140/90 mmHg, despite a therapeutic strategy that includes appropriate lifestyle measures, plus a diuretic and two other antihypertensive drugs belonging to different classes at adequate doses.1 The definition of RHT has been quite arbitrary, a fact reflected on various definitions of ideal…
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Author(s):
Astrid Hubert
,
Andreas Seitz
,
Valeria Martínez Pereyra
,
et al
Added:
3 years ago
Coronary artery spasm (CAS) is an established cause for anginal chest pain, the cardinal symptom of myocardial ischaemia, in patients with angiographically unobstructed coronary arteries. Evidence from large clinical studies has revealed that about 50% of patients undergoing diagnostic coronary angiography for suspected coronary artery disease (CAD) had either normal or near normal coronary…
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Home Blood Pressure Monitoring
Author(s):
Jacob George
,
Thomas M MacDonald
Added:
3 years ago
Article
Author(s):
Markus P Schlaich
,
Murray D Esler
Added:
3 years ago
The pathogenesis of primary hypertension is multifactorial. However, the sympathetic nervous system plays an important role in circulatory and metabolic control and has clearly been established as a major contributor to the development of hypertension, with blood pressure elevation being initiated and sustained by elevated sympathetic nervous activity. Increased sympathetic outflow to the heart…
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Author(s):
Peter M Nilsson
Added:
3 years ago
Some cardiovascular (CV) risk-prone patients are easy to recognise, for example following manifestations of cardiovascular disease (CVD), coronary artery bypass graft (CABG) or percutaneous transluminal coronary angioplasty (PTCA) interventions, and they deserve appropriate risk-factor control for secondary prevention, including blood pressure (BP) lowering. However, many other at-risk patients…
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Author(s):
Michel Burnier
Added:
3 years ago
Hypertension (HTN) is the most prevalent cardiovascular risk factor in developed and developing countries.1 According to most recent guidelines, the goal of HTN management should be to reduce blood pressure (BP) to <140/90mmHg and even lower in patients with a high cardiovascular risk in order to lower the incidence of cardiovascular events such as stroke, myocardial infarction, congestive…
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Author(s):
Peter M Nilsson
Added:
3 years ago
Some cardiovascular (CV) risk-prone patients are easy to recognise, for example following manifestations of cardiovascular disease (CVD), coronary artery bypass graft (CABG) or percutaneous transluminal coronary angioplasty (PTCA) interventions, and they deserve appropriate risk-factor control for secondary prevention, including blood pressure (BP) lowering. However, many other at-risk patients…
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Author(s):
Francesco P Cappuccio
Added:
3 years ago
Hypertension is a major independent risk factor for cardiovascular (CV) diseases, including cardiac death, coronary heart disease, heart failure, stroke and chronic kidney disease. Therefore, early diagnosis, prevention and optimal management of hypertension is essential.1 Hypertension poses a growing public health burden: the number of adults with elevated blood pressure (BP) increased from 594…
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Author(s):
Felix Mahfoud
Added:
1 year ago
In this short late-breaking interview, Prof Felix Mahfoud (Saarland University Hospital, DE) discusses the 3-year efficacy outcomes of the SPYRAL HTN-ON MED Pilot Study (NCT02439775). The global clinical study, presented at ACC.22, tested the long-term effect of renal denervation (Symplicity Spyral™ multi-electrode renal denervation system, Medtronic Vascular) on blood pressure reduction in…
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