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Author(s): Alan S Katz Added: 3 years ago
Computed tomography (CT) of the heart combines X-ray images with the aid of a computer to generate cross-sectional views of the body. Cardiac CT uses advanced CT technology with or without intravenous contrast dye to visualise cardiac anatomy, coronary circulation, and the great vessels. Cardiac CT is especially useful in evaluating the myocardium, coronary arteries, pulmonary veins, thoracic… View more
Author(s): Jyrki T Kuikka Added: 3 years ago
Myocardial perfusion imaging (MPI) using combined computed tomography (CT) and single-photon emission CT (SPECT) systems plays an important role in the management of patients with coronary artery disease (CAD).1–4 The method can be used to assess myocardial perfusion and left ventricular function simultaneously. It is an especially valuable tool for assessing short-term risk of CAD, thus… View more
Author(s): Lukas Lehmkuhl , Matthias Gutberlet , Stefan Nitzsche , et al Added: 3 years ago
Since the introduction of multislice computed tomography (MSCT) in 1998, non-invasive cardiac imaging has developed rapidly. In the recent past, two different objectives can be observed in the technological development of cardiac MSCT. On the one hand, the number of detector rows was increased up to 320 in single-source scanners in order to ensure simultaneous coverage of the entire heart with a… View more
Author(s): Andreas H Mahnken , Joachim E Wildberger , Peter R Seidensticker Added: 3 years ago
Coronary artery disease (CAD) represents a relevant economic burden to modern medicine. In 2003 more than 1.41 million diagnostic coronary angiograms and an additional 1.24 million percutaneous coronary angioplasties were performed in the US alone.1 While coronary angiography is considered the gold standard for diagnosing CAD, several non-invasive techniques have been evaluated for assessing CAD… View more
Author(s): Paul Schoenhagen Added: 3 years ago
Since its introduction into medical imaging in the 1970s,1 computed tomography (CT) has significantly contributed to novel diagnostic approaches in a wide variety of clinical conditions across multiple medical specialities. However, increased use has also been associated with a significant increase in radiation exposure, with uncertain long-term implications.2,3 Cardiovascular multidetector… View more
Author(s): Konstantinos Toutouzas , Antonios Karanasos , Dimitris Tousoulis Added: 3 years ago
Acute coronary syndromes (ACS) comprise a major cause of morbidity and mortality. The almost-exclusive cause of ACS, including unstable angina, acute myocardial infarction (AMI) with or without ST-segment elevation, and sudden cardiac death, is atherothrombosis. Pilot pathological studies have identified the pathophysiological processes implicated in the destabilisation and thrombosis of… View more
Author(s): Maxime Teisseire , Jérôme Caudron , Jean-Nicolas Dacher Added: 3 years ago
In patients with severe aortic stenosis (aortic valve area <1cm2 or <0.6cm2/m2) and high surgical risk (haemodynamic instability or significant co-morbidities), surgical aortic valve replacement is often rejected and, unfortunately, balloon valvuloplasty cannot provide a sustained improvement. Percutaneous heart valve (PHV) implantation is an excellent alternative treatment in such cases… View more
Author(s): Hug Cuéllar-Calàbria , Río Aguilar-Torres Added: 3 years ago
Cardiac computed tomography (CT) has become a useful non-invasive technique for the study of cardiac pathology in daily clinical practice due to its high negative predictive value for detecting coronary artery disease (CAD). Its established main role in clinical practice is ruling out CAD in symptomatic patients with intermediate risk of CAD, who remain a diagnostic problem after other non… View more
Author(s): Jelmer Westra Added: 3 years ago
Dr Jelmer Westra (Aarhus University Hospital, Aarhus, DK) discusses CT-QFR or myocardial perfusion imaging in patients with coronary stenosis on CTA. Questions: 1. Can you remind us of the Dan-NICAD study? 2. What was the rationale of the sub-study you conducted? 3. What was the design of the sub-study? 4. What were your findings? 5. What are the benefits of CT-QFR for patients with… View more
Author(s): Santo Dellegrottaglie , Pierluigi Costanzo , Stefania Paolillo , et al Added: 3 years ago
In Europe, subjects >65 years of age currently constitute 17% of the entire population, with some variations between countries (see Figure 1).1 More importantly, as a consequence of the ageing population, elderly subjects are expected to account for 30% of the European population by 2050. Currently, cardiovascular disease is the major cause of death in Europe (~20% of all causes) and more than… View more