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Author(s): Jaskanwal D Sara , Takumi Toya , Riad Taher , et al Added: 3 years ago
Heart failure (HF) affects more than 6 million people in the US and results in more than 1 million hospitalisations per year.1 In patients aged ≥65 years, there are more hospitalisations for a primary diagnosis of HF than any other condition.2 HF is a debilitating illness, associated with significant morbidity and mortality, rehospitalisation and societal costs.3 Current guidelines and position… View more
Author(s): Gilles W De Keulenaer , Dirk L Brutsaert Added: 3 years ago
Definitions and Historical Considerations – The Misleading Role of Ejection Fraction Chronic heart failure (CHF) is a heterogeneous syndrome with a complex pathophysiology. Although many different definitions for heart failure exist, we prefer the following: “a clinical syndrome characterised by symptoms and signs of increased tissue/organ water and decreased tissue/organ perfusion. Regardless… View more
Author(s): Charles Knight , Saidi Mohiddin Added: 3 years ago
The management of patients with hypertrophic cardiomyopathy (HCM) requires expertise in heart failure, cardiac imaging, electrophysiology, genetic testing and counselling, and in techniques that reduce left ventricular outflow tract obstruction (LVOTO). Following the initial description of alcohol septal ablation (ASA) in 1995,1 it has gained rapid acceptance and is now the most commonly chosen… View more
Author(s): Konstantinos Bratis Added: 3 years ago
Takotsubo syndrome (TTS) is an acute, profound, but reversible heart failure syndrome, usually but not always triggered by physical or emotional stress. To date, the exact pathogenic mechanism of this syndrome remains unclear; however, several hypotheses involving vascular mechanisms (i.e. abnormal coronary epicardial or microvascular vasoreactivity),1-3 endocrine and gender-related mechanisms (i… View more
Author(s): Athanasios Charalampopoulos , J Simon R Gibbs Added: 3 years ago
Abstract Pulmonary hypertension is a relatively common finding in patients with left heart disease and lung hypoxic disease. Nonetheless, some types of pulmonary hypertension, such as pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension, are rare. Despite the rarity of these diseases their impact on patients' lives and healthcare system is significant because of… View more
Author(s): Douglas Ewan Cannie , Mohammed Majid Akhtar , Perry Elliott Added: 3 years ago
Heart failure is a global health challenge, affecting 1–2% of the population and up to an estimated 64 million people worldwide.1,2 In the UK, just under 1 million people have heart failure, with approximately 350 new diagnoses each year per 100,000 population.3 The lifetime risk of developing heart failure at 55 years of age is 33% for men and 28% for women.4 The heart failure population is… View more
Author(s): Cesare Rusconi Added: 3 years ago
With the widespread availability of non-invasive bedside assessment of ventricular function by echocardiography in the last two decades the paradigm of heart failure (HF), presumed to be usually due to an impaired left ventricular (LV) systolic function, has been challenged by the finding that about half of patients suffering from HF syndrome exhibit a normal LV ejection fraction (LVEF), and the… View more
Author(s): Helen O'Brien , Rose Anne Kenny Added: 3 years ago
One of the greatest achievements of public health in the twentieth century has been the almost doubling of life expectancy in the Western world. Yet this now ageing population brings new challenges, as the prevalence of little-understood geriatric conditions increases, together with the rising prevalence of age-related disorders, such as syncope. The definition of syncope, as outlined by the… View more