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Author(s): WY Wandy Chan , Richard W Troughton Added: 3 years ago
Acute coronary syndromes (ACS) and acute pulmonary embolism (APE) are leading causes of hospital admission and mortality. Accurate risk stratification is important for both conditions to guide management and the use of therapies that lead to improved outcomes. Acute Coronary Syndromes Despite a steady decline in developed countries, ischaemic heart disease is still the leading cause of death… View more
Author(s): Patrick W Serruys Added: 3 years ago
In the Cardiology Masters section of European Cardiology Review, we bring you an insight into the career of a key contributor to the field of cardiology. In this edition, we feature Dr Patrick Serruys, professor of cardiology at the National Heart and Lung Institute at Imperial College, London, UK. The hippopotamus and left ventricular contractility In 1947, shortly after my birth, my family… View more
Author(s): Iskren Garvanski , Iana Simova , Lazar Angelkov , et al Added: 3 years ago
AF is the most common sustained arrhythmia in clinical routine, and is associated with cardiovascular and cerebrovascular complications, dementia and mortality.1 Pulmonary vein isolation (PVI) in patients with symptomatic AF has become a well-established treatment option.2,3 High acute success rates are achievable, but durable efficacy of previously successful PVIs for AF still remains a… View more
Author(s): Vibeke Marie Almaas , Jan Peder Amlie Added: 3 years ago
Hypertrophic cardiomyopathy (HCM) is a familial disease with a disease-causing mutation in the genes encoding structural components of the cardiac muscle sarcomere in about 60% of cases.1 In a general population of healthy young adults, the prevalence is 1:500.2 The penetrance is incomplete and age-related with a wide clinical spectrum.1 Many patients have normal life expectancy, some die… View more
Author(s): Otto Kamp , Gabriel Valocik Added: 3 years ago
Background Echocardiography has evolved into the most predominant diagnostic imaging technique in cardiology. Over the last five decades the diagnostic capability of echocardiography has increased dramatically from M-mode to two-dimensional (2-D) imaging. Recent advances in ultrasound instrumentation and computer technology have led to three-dimensional (3-D) echocardiography, introducing a new… View more
Author(s): Konstantinos Bratis Added: 3 years ago
Takotsubo syndrome (TTS) is an acute, profound, but reversible heart failure syndrome, usually but not always triggered by physical or emotional stress. To date, the exact pathogenic mechanism of this syndrome remains unclear; however, several hypotheses involving vascular mechanisms (i.e. abnormal coronary epicardial or microvascular vasoreactivity),1-3 endocrine and gender-related mechanisms (i… View more
Author(s): Giuseppe Gullace , Hassan Khalaf Added: 3 years ago
The endothelium, which was initially considered to be a semipermeable barrier separating lumen from vessel wall, is now recognised as a complex endocrine organ responsible for a variety of physiological processes vital for vascular homeostasis. These include the regulation of vascular tone, luminal diameter and blood flow; haemostasis and thrombolysis; platelet and leucocyte vessel-wall… View more
Author(s): David D Daly Jr , Michael R Gold Added: 3 years ago
Interventricular conduction delay is common in patients with systolic heart failure (HF) and has been associated with a poor prognosis amongst these patients.1 Abnormal ventricular depolarization results in prolonged ventricular activation time and increased myocardial tension thus increasing myocardial oxygen consumption and decreasing ventricular diastolic filling time. In addition,… View more