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Author(s):
Giuseppe Gullace
,
Hassan Khalaf
Added:
3 years ago
The endothelium, which was initially considered to be a semipermeable barrier separating lumen from vessel wall, is now recognised as a complex endocrine organ responsible for a variety of physiological processes vital for vascular homeostasis. These include the regulation of vascular tone, luminal diameter and blood flow; haemostasis and thrombolysis; platelet and leucocyte vessel-wall…
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Author(s):
Ephraim B Beck
,
Claudia Walther
,
Antje Körner
,
et al
Added:
3 years ago
In developed countries cardiovascular diseases – including coronary heart disease with acute myocardial infarction and ischaemic heart failure, stroke and chronic cerebrovascular disease, aortic aneurysm, valve disease and peripheral arterial occlusive disease – are by far the main cause of death. Since first cardiovascular events are usually seen in mid-life and old age, atherosclerosis has long…
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Author(s):
Esmee ME Bovee
,
Martha Gulati
,
Angela Maas
Added:
2 years ago
Author(s):
Domenico D’Amario
,
Stefano Migliaro
,
Josip A Borovac
,
et al
Added:
3 years ago
The ancient rite of smoking dates back thousands of years, and tobacco smoking has been largely ingrained in our civilization since the arrival of Europeans to the Americas in the 16th century. For a long time, cigarette smoking was perceived as a symbol of wealth, glamour and sophistication, whereas nowadays it is largely recognised as the first preventable or modifiable cause of common diseases…
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Added:
3 years ago
Dr Kieran Docherty (University of Glasgow, Glasgow, UK) discusses the results of the DAPA-HF trial.
In the DAPA-HF trial, the SGLT2 inhibitor, dapagliflozin reduced the risk of worsening heart failure (HF) and death in patients with HF and reduced ejection fraction (HFrEF). Its use was examined to assess if the benefit was consistent in relation to background HF therapy.
Recorded remotely…
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Author(s):
Sayaka Shimada
,
Maki Komiyama
,
Hiromichi Wada
,
et al
Added:
3 years ago
Topic: 5. Secondary Prevention of Cardiovascular Disease.
Introduction and Objectives
It is reported that 3 months of professional smoking cessation treatment achieves an initial smoking cessation rate of 80%. However, a 1 year cessation rate decreases to approximately 50%. The most common causes of relapse are weight gain, stress, and nicotine withdrawal symptoms. Relapse prevention is…
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Author(s):
Sivabaskari Pasupathy
,
Rosanna Tavella
,
Simon McRae
,
et al
Added:
3 years ago
Early coronary angiography performed during acute MI (AMI) identifies an occluded vessel in most patients with ST elevation MI (STEMI)1 and less frequently in those with non-STEMI;2 however, ≥90 % of patients with AMI have evidence of obstructive coronary artery disease.3 For these patients with overt coronary artery disease (CAD), the benefits of reperfusion strategies and cardioprotective…
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Author(s):
Mark CS Hall
,
Johan EP Waktare
Added:
3 years ago
Introduction
Since the inception of cardiac pacing, the favoured site has been the right ventricular apex (RVA). The RVA is popular as it is usually straightforward, provides stable lead position and is associated with few complications.
A critical re-evaluation of this practice is occurring, however. There is accumulating evidence that RVA pacing causes adverse effects on left ventricular (LV)…
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Author(s):
Harry Crijns
Added:
3 years ago
Atrial fibrillation (AF) is the most common arrhythmia. It takes the form of a rapid and irregular heartbeat and pulse rate, and predominantly affects the older population. AF is particularly prevalent in patients with cardiac disease. Patients suffering from AF largely fall into two categories: the elderly with cardiovascular (CV) complications or the young with intrinsic electrical disease. An…
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Author(s):
Christos-Konstantinos Antoniou
,
Panagiota Manolakou
,
Nikolaos Magkas
,
et al
Added:
3 years ago
Cardiac resynchronisation therapy (CRT) has been a cornerstone in the treatment of select advanced heart failure cases since its introduction to our armamentarium in the early 2000s.1 Indeed, 30–60% of advanced heart failure patients exhibit evidence of dyssynchrony, when defined electrocardiographically or mechanically.2–4 The latter is a consequence of the former. CRT has several unique…
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