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Author(s): Douglas Ewan Cannie , Mohammed Majid Akhtar , Perry Elliott Added: 3 years ago
Heart failure is a global health challenge, affecting 1–2% of the population and up to an estimated 64 million people worldwide.1,2 In the UK, just under 1 million people have heart failure, with approximately 350 new diagnoses each year per 100,000 population.3 The lifetime risk of developing heart failure at 55 years of age is 33% for men and 28% for women.4 The heart failure population is… View more

Heart Failure
Clinical Management of Non-alcoholic Steatohepatitis
Author(s): Carlos Millán-Rodríguez , Carlos Palacios Castelló , María de Regla Caballero-Valderrama , et al Added: 4 months ago

Prevention & Chronic Conditions
European Society of Cardiology Highlights: Late-breaking Trials – COVID-19
Author(s): Maki Komiyama , Koji Hasegawa Added: 2 years ago

Anticoagulation

COVID-19
The Coronavirus Disease 2019 Outbreak Highlights the Importance of Sex-sensitive Medicine
Author(s): Angela Maas , Sabine Oertelt-Prigione Added: 3 years ago
While 2020 is only halfway through, we have already experienced a historical year in global healthcare with a high societal impact. When the first severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections were reported in China at the end of 2019, few people realised we would all be affected by a global pandemic several months later. Women are less susceptible than men to many… View more

Demographic
Cardiovascular Management of Adults with Marfan Syndrome
Author(s): Yukiko Isekame , Sabiha Gati , Jose Antonio Aragon-Martin , et al Added: 3 years ago
Marfan syndrome (MFS) is a disease in which connective tissue becomes weak secondary to fibrillin-1 mutations, resulting in aortic dilatation, aneurysm formation, aortic dissection, aortic regurgitation and mitral valve prolapse (MVP; see Table 1). Epidemiology MFS is an autosomal dominant condition: 75 % of all patients inherit the condition from one affected parent and 25 % are affected as… View more

Vascular Disease and Surgery

Electrophysiology & Arrhythmia
Author(s): Vibeke Marie Almaas , Jan Peder Amlie Added: 3 years ago
Hypertrophic cardiomyopathy (HCM) is a familial disease with a disease-causing mutation in the genes encoding structural components of the cardiac muscle sarcomere in about 60% of cases.1 In a general population of healthy young adults, the prevalence is 1:500.2 The penetrance is incomplete and age-related with a wide clinical spectrum.1 Many patients have normal life expectancy, some die… View more

Heart Failure

MI/ACS
Author(s): Reginald Liew Added: 3 years ago
Sudden cardiac death (SCD) can be defined as unexpected death that occurs within one hour of the onset of symptoms or during sleep in a person who was previously stable. The mode of death, which may be due to an arrhythmic or non-arrhythmic cause, depends on the underlying cardiovascular abnormality (mechanical or electrical substrate). SCD remains a major public health problem worldwide and is… View more

Imaging & Diagnostics
Author(s): Christos-Konstantinos Antoniou , Polychronis Dilaveris , Panagiota Manolakou , et al Added: 3 years ago
Ventricular repolarization, as opposed to depolarization, is not a triggered phenomenon following an orderly sequence, hence the dissimilarity between their inscribed electrocardiographic waves; rather, ventricular myocytes repolarize at a time and rate determined by their intrinsic electrophysiological properties (relative concentration of ion channel types and isoforms), as well as by the… View more

Electrophysiology & Arrhythmia
Author(s): Eric Larose , Olivier F Bertrand Added: 3 years ago
Cardiovascular magnetic resonance (CMR) has found widespread use as an important tool in the cardiologists' armamentarium for several years now, mainly because of superior diagnostic accuracy and ability to perform complete anatomical and functional assessment in a single study without ionising radiation. The following will summarise specific uses of CMR for the interventional cardiologist. … View more

Imaging & Diagnostics
Author(s): John G Coghlan Added: 3 years ago
The pace of progress in the field of pulmonary arterial hypertension (PAH) continues to be breathtaking. In the past couple of years two new oral agents have been granted licences. Fourteen major international drug trials are underway, many evaluating the role of combination therapies, and at least three agents (simvastatin, imatinib and aviptadil) are undergoing proof of concept studies in… View more

Prevention & Chronic Conditions