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Application of CD271+ Human Bone Marrow-derived Stem Cells for Ischaemic Heart Disease Therapy
Author(s):
Ali Ghodsizad
,
Mina Farag
,
Matthias Loebe
,
et al
Added:
3 years ago
Article
Author(s):
Shu Nakao
,
Dai Ihara
,
Koji Hasegawa
,
et al
Added:
3 years ago
Induced Pluripotent Stem Cells and Their Potential Applications
Induced pluripotent stem cells (iPSCs) are generated from somatic cells, such as skin fibroblasts, by ectopic expression of defined reprogramming factors. Within a few years of the first report of the generation of mouse iPSCs, several laboratories reportedly reproduced these cells using other cell types and species using similar…
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Author(s):
Gustav Steinhoff
Added:
3 years ago
Cell therapy for myocardial regeneration is an exciting new field of medical research that has the potential to revolutionise cardiovascular medicine. Despite significant improvements in emergency treatment, myocardial infarction (MI) leads to a net loss of contractile tissue in many patients with coronary artery disease (CAD). Often, this is the beginning of a downward spiral towards congestive…
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Author(s):
Hans-Michael Klein
Added:
3 years ago
An increasing number of patients survive acute myocardial infarction. Surgical and interventional revascularisation of the ischaemic myocardium can treat angina, reduce risk of myocardial infarction and improve the function of the viable myocardium. However, the therapeutic possibilities in end-stage heart failure patients are limited. This article investigates alternative treatment options such…
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Author(s):
Gustav Steinhoff
Added:
3 years ago
Cell therapy for myocardial regeneration is an exciting new field of medical research that has the potential to revolutionize cardiovascular medicine. Despite significant improvements in emergency treatment, myocardial infarction leads to a net loss of contractile tissue in many patients with coronary artery disease. Often, this is the beginning of a downward spiral towards congestive heart…
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Author(s):
Daniel Alejandro Lerman
,
Nasri Alotti
,
Kiddy Levente Ume
,
et al
Added:
3 years ago
Acute myocardial infarction (AMI) is still a major public health problem worldwide, causing high rates of morbidity and mortality. In the United States, nearly one million patients suffer from AMI each year.1 In the UK, around 80,000 people died from coronary heart disease (CHD) in 2010.2
The current approach to the treatment of myocardial infarction involves early revascularisation with…
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Author(s):
Kevin Cheng
,
Ranil de Silva
Added:
3 years ago
Refractory angina (RA) is defined as chronic angina-type chest pain (duration ≥ 3 months) associated with reversible ischaemia that persists despite optimal medical, interventional and surgical management.1
The clinical burden of RA is growing due to an ageing population and improved survival from coronary artery disease (CAD). Estimates suggest that in the US between 600,000 and 1.8 million…
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Joseph C. Wu
Research Area(s) / Expertise:
Job title: Director
Author
Cell-specific Mathematical Modelling of hiPSC-CMs and Its Potential for Prediction of Drug Testing
Author(s):
Hirohiko Kohjitani
,
Shigeya Koda
,
Yukiko Himeno
,
et al
Added:
3 years ago
Article
Author(s):
Tomoaki Ishida
,
Tomoe Ueyama
,
Ai Baba
,
et al
Added:
2 years ago