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Author(s): Vibeke Marie Almaas , Jan Peder Amlie Added: 3 years ago
Hypertrophic cardiomyopathy (HCM) is a familial disease with a disease-causing mutation in the genes encoding structural components of the cardiac muscle sarcomere in about 60% of cases.1 In a general population of healthy young adults, the prevalence is 1:500.2 The penetrance is incomplete and age-related with a wide clinical spectrum.1 Many patients have normal life expectancy, some die… View more

Heart Failure

MI/ACS
Author(s): Augusto Vicario , Gustavo H Cerezo Added: 3 years ago
Heart-brain interaction is an indisputable fact. The connection between vascular risk factors and/or cardiovascular disease and cognitive impairment and dementia has been supported by countless publications in the past 30 years. The most important studies concluded that vascular brain injury exacerbates cognitive ageing, and increases the risk for dementia both in its vascular type and in its… View more

Prevention & Chronic Conditions
View from the Thoraxcenter: EuroPCR 23 Late-breaking Science Preview
Author(s): Nicolas M Van Mieghem , Joost Daemen Added: 11 months ago
Join Prof Nicolas Van Mieghem and Dr Joost Daemen, interventional experts from the Thoraxcenter at Erasmus MC in Rotterdam, as they provide a comprehensive preview of the late-breaking trials and studies that will be presented at EuroPCR 2023. In this dynamic episode, they offer valuable insights into the latest developments in interventional clinical and research science. Studies include:… View more

Intervention
Author(s): Marc E Wolf , Michael G Hennerici Added: 3 years ago
Aetiological Classification of Stroke Precise analysis of stroke subtypes is important for clinical treatment decisions and prognostic evaluation of patients leading to adapted individual patient management. The most widely used system of aetiological ischaemic stroke classification is the Trial of Org 10172 in Acute Stroke Treatment (TOAST) classification, proposed in 1993 for an acute stroke… View more

Electrophysiology & Arrhythmia

Prevention & Chronic Conditions
Drug-eluting Balloons in Coronary Artery Disease
Author(s): Anouar Belkacemi , Pierfrancesco Agostoni , Michiel Voskuil , et al Added: 3 years ago
In the past few decades, major progress has been made in the percutaneous treatment of coronary artery disease. Initially, the emergence of balloon angioplasty offered an alternative option for coronary revascularisation. However, abrupt closure and restenosis caused by elastic recoil, neointimal hyperplasia and late remodelling were major drawbacks of balloon angioplasty.1 The use of drug… View more

Imaging & Diagnostics

Prevention & Chronic Conditions
ESC 22: Milvexian in Addition to Aspirin ＆ Clopidogrel for Secondary Stroke
Author(s): Mukul Sharma Added: 1 year ago
ESC Congress 22 — We are joined onsite by Dr Mukul Sharma (Mcmaster University, CA) to discuss the findings of the AXIOMATIC-SSP (NCT03766581) trial. This study aimed to evaluate the effectiveness of oral Factor XIa inhibitor milvexian in addition to aspirin and clopidogrel as compared to standard therapies in secondary stroke prevention. 2366 participants were involved in the trial, and were… View more

Anticoagulation

Prevention & Chronic Conditions
Author(s): Bruno Scheller , Bodo Cremers , Stephanie Schmitmeier , et al Added: 3 years ago
Coronary angioplasty was introduced to clinical practice by Andreas Grüntzig in 1977.1 In the coronary field, the most important improvement in angioplasty has been achieved with the introduction of stents. A significant proportion of the complex modern coronary interventional techniques rely on stenting. Stenting overcomes recoil and dissections but not restenosis due to neointimal proliferation… View more

Intervention
Author(s): Myriam Edjlali-Goujon , Daniel Alison Added: 3 years ago
Digital ischaemia is an uncommon pathology, with an incidence of two cases per 100,000 people per year.1 Diagnosis is mainly based on clinical symptoms: the patient presents a painful digital extremity with signs of ischaemia (blue finger) or even necrosis. Clinical context and medical history are also important to determine the aetiology of digital ischaemia. The role of imaging modalities is… View more

Imaging & Diagnostics

MI/ACS
Author(s): Mai Tone Lønnebakken , Eva Gerdts Added: 3 years ago
Coronary artery disease (CAD) remains a diagnostic challenge, even though there are several diagnostic techniques available for the detection of ischaemia – assessed either as function or perfusion abnormalities or directly by demonstrating anatomical coronary stenoses.1 An overview of different non-invasive modalities used in the diagnosis of myocardial ischaemia and their average sensitivity… View more

Imaging & Diagnostics

Prevention & Chronic Conditions
Slow Coronary Blood Flow: Pathogenesis and Clinical Implications
Author(s): Andrea Aparicio , Javier Cuevas , César Morís , et al Added: 2 years ago

Vascular Disease and Surgery