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Author(s): Eric Prystowsky , Jean-Yves Le Heuzey Added: 3 years ago
For decades, conventional wisdom suggested that sinus rhythm was preferred over rate control in the treatment of patients with atrial fibrillation (AF). Recent randomised trials have been unable to substantiate this viewpoint, and the occurrence of serious outcomes for patients has been similar for both treatment strategies.1,2 More specifically, several large, randomised, prospective clinical… View more

Heart Failure

Electrophysiology & Arrhythmia
Author(s): Lori L McMullan , Gaston Vergara , Nassir F Marrouche Added: 3 years ago
Atrial fibrillation (AF) and heart failure (HF) are two disease conditions that are intimately intertwined, both pathophysiologically and clinically. Currently, over 2.3 million people in North America and 4.5 million in the EU have AF, making it the most common arrhythmia encountered in clinical practice.1,2 It is expected that by 2050 there will be over 10 million people with AF.3 The estimated… View more

Imaging & Diagnostics

Heart Failure
Author(s): Philippe Chevalier Added: 3 years ago
Atrial fibrillation (AF), characterised by rapid and irregular activation of the atrium, is the most common arrhythmia in clinical practice, and 2.3 million people in North American and 4.5 million people in the EU are estimated to have paroxysmal or persistent AF.1 An estimated 0.4–1% of the general population are affected with AF,1 with prevalence increasing to nearly 10% in the octogenarian… View more

Electrophysiology & Arrhythmia
Author(s): Gerald V Naccarelli , Deborah L Wolbrette , Soraya Samii , et al Added: 3 years ago
Currently available antiarrhythmic drugs for the treatment of atrial fibrillation are limited in their efficacy and have potential for adverse effects, including torsade de pointes. With the aging of the population, the incidence of atrial fibrillation will double in frequency over the next 15 years. Thus, more effective and safer antiarrhythmic drugs for the treatment of atrial fibrillation are… View more

Electrophysiology & Arrhythmia
Author(s): Akihiko Nogami Added: 3 years ago
No apparent structural abnormality is identified in approximately 10% of all sustained monomorphic ventricular tachycardias (VTs) in the US1 and in 20% of those in Japan.2 These VTs are referred to as ‘idiopathic’. Idiopathic VTs usually occur in specific locations and have specific QRS morphologies, whereas VTs associated with structural heart disease have a QRS morphology that tends to indicate… View more

Electrophysiology & Arrhythmia
Author(s): A John Camm , Craig Pratt , Silvia Priori Added: 3 years ago
Atrial fibrillation (AF) is the most common cardiac arrhythmia, having an estimated combined prevalence of 6.8 million in the EU and the US.1,2 It is characterised by unco-ordinated atrial activation followed by the deterioration of mechanical function, which results in disturbances to sinus rhythm and ventricular rate.2 An increased risk of heart failure (HF), thrombo-embolism, cardiomyopathy, a… View more

Electrophysiology & Arrhythmia
Author(s): Katrina Mountfort , Karl-Heinz Kuck , Richard Schilling Added: 3 years ago
Atrial fibrillation (AF) is the most common arrhythmia and is associated with increased risk of stroke, heart failure and mortality.1 Following increased therapeutic options for AF, an update in guidelines for management of AF has been published. A symposium, chaired by Karl- Heinz Kuck, Hamburg, Germany, was held at the European Society of Cardiology (ESC) congress in Paris on the 2nd September… View more

Standards & Guidelines

Electrophysiology & Arrhythmia
Author(s): Neil Davidson , Julian Hobbs Added: 3 years ago
The right and left atria are two complex cardiac chambers with the role of collecting venous blood from the body and the lungs, respectively, before contracting to augment the passive filling of the ventricles. This contraction is initiated and co-ordinated by the electrical conduction system of the heart. An important abnormality of heart rhythm is atrial fibrillation (AF), affecting 1–2% of the… View more

Electrophysiology & Arrhythmia
Author(s): Carlo Pappone , Vincenzo Santinelli Added: 3 years ago
Atrial fibrillation (AF) is the most common cardiac arrhythmia and is associated with an increased risk of morbidity and mortality.1 Despite important advances in its treatment, AF remains an independent predictor of both morbidity and mortality. Morbidity is related to frequent hospitalisations due to debilitating symptoms, heart failure (HF), stroke and systemic thromboembolism. The rise in… View more

Electrophysiology & Arrhythmia
Author(s): Richard Sutton , Michele Brignole Added: 3 years ago
The implantable loop recorder (ILR) is a small device manufactured by Medtronic Inc., Minneapolis, MN, which is implanted subcutaneously close to the heart. It has the ability to record the electrical activity of the heart, store rhythm disturbances within set parameters and can be triggered by the patient to store events. The loop recorder is a device with a high diagnostic yield and offers… View more

Electrophysiology & Arrhythmia

Intervention