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Author(s):
Haruka Ebi
,
Masafumi Funamoto
,
Yoichi Sunagawa
,
et al
Added:
3 years ago
Young Investigator Award
Topic: 3. Heart Failure and Cardiomyopathy
Introduction and Objectives
Maladaptive hypertrophy is being recognized as a critical event during the development of heart failure. We screened natural compounds purified from fruits library and found that Nobiletin, contained in the peel of Citrus depressa, represses phenylephrine-induced hypertrophic responses in…
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Author(s):
Masafumi Funamoto
,
Yoichi Sunagawa
,
Yasufumi Katanasaka
,
et al
Added:
3 years ago
Topic: 3. Heart Failure and Cardiomyopathy
Introduction and Objectives
An intrinsic histone acetyltransferase (HAT), p300, is required for acetylation and the transcriptional activity of GATA4, as well as for pathological left ventricular hypertrophy (LVH) and the development of heart failure (HF) in vivo. Many studies of histone modification have been performed within the flexible tails of…
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Author(s):
Miriam Reiter
,
Tobias Reichlin
,
Raphael Twerenbold
,
et al
Added:
3 years ago
Acute myocardial infarction (AMI) is a major cause of morbidity and mortality worldwide. Accordingly, prompt identification of patients with AMI is critical, as established therapies exist that are of proven benefit.1,2 More than 15 million patients per year present to emergency departments with symptoms compatible with acute myocardial ischaemia in the US and Europe; only 20–30%, however, are…
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Author(s):
Angela Maas
,
Sabine Oertelt-Prigione
Added:
3 years ago
While 2020 is only halfway through, we have already experienced a historical year in global healthcare with a high societal impact. When the first severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections were reported in China at the end of 2019, few people realised we would all be affected by a global pandemic several months later.
Women are less susceptible than men to many…
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Author(s):
Christian Mueller
,
Evangelos Giannitsis
,
James L Januzzi
Added:
3 years ago
Improvements in the Early Diagnosis of Acute Myocardial Infarction using a Cardiac Troponin T-high Sensitive Assay
In the first talk, Christian Mueller, a Professor at the University Hospital in Basel, discussed the unmet needs of current troponin assays and the improvements made in the early diagnosis of acute myocardial infarction (AMI) using the latest cardiac troponin T-high sensitive (cTnT…
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Author(s):
Harlokesh Narayan Yadav
,
Sadia Shah
Added:
11 months ago
Author(s):
Hidemichi Takai
,
Yoichi Sunagawa
,
Masafumi Funamoto
,
et al
Added:
2 years ago
Author(s):
Yoichi Sunagawa
,
Ayumi Katayama
,
Masafumi Funamoto
,
et al
Added:
2 years ago
Current Recommendations for Interpretation of the Highly Sensitive Troponin T Assay for Diagnostic,…
Author(s):
Evangelos Giannitsis
,
Hugo A Katus
Added:
3 years ago
Article
Author(s):
Robert Voswinckel
,
Ralph T Schermuly
,
Norbert Weissmann
,
et al
Added:
3 years ago
Pulmonary arterial hypertension (PAH) is a chronic, progressive disease defined by increasing pulmonary vascular resistance and pulmonary arterial pressure, ultimately leading to right heart failure. The life expectancy of patients with PAH who do not receive appropriate treatment is dramatically reduced. Guidelines for the diagnosis and treatment of PAH have been established by the American…
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