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Author(s): Tonje A Aksnes , Markus P Schneider , Sverre E Kjeldsen , et al Added: 3 years ago
The renin–angiotensin system (RAS) has an important role in many cardiovascular diseases, such as hypertension, left ventricular hypertrophy, atherosclerosis and heart failure, and lately its relationship with cardiac arrhythmias has also been investigated.1 Atrial fibrillation is the most frequently occurring sustained cardiac arrhythmia and its prevalence doubles with each advancing decade of… View more
Job title: Professor of Medicine
Dr Weber is Professor of Medicine and Associate Dean for Research at the SUNY Downstate College of Medicine in Brooklyn, New York. He received his medical degree from Sydney University in Australia.His career has been focused primarily on hypertension and preventive cardiology. Dr Weber was one of the founders of The American Society of Hypertension and has served as its President. He is a… View more
Specialist in: cardiology, internal medicine, arterial hypertension, clinical pharmacology (4 certified specializations). Education: Medical University of Warsaw (MUW), MD, PhD. Scientific and clinical internships: Medical Faculty, Utrecht University, Netherlands, Medical Faculty, Amsterdam University, Netherlands, Internal Medicine Department, Gaffree e Guinle University, Rio de Janeiro,… View more
Author(s): Giuliano Tocci , Lorenzo Castello , Massimo Volpe Added: 3 years ago
The renin–angiotensin system (RAS) has a key role in the maintenance of cardiovascular (CV) homeostasis, and water and electrolyte metabolism in healthy subjects.1 By contrast, the excess of angiotensin II in several diseases represents a pathophysiological mechanism that can promote or even accelerate atherosclerotic processes, cardiac and vascular hypertrophy, and kidney disease.1 In particular… View more
Author(s): Laurent Fauchier Added: 3 years ago
Hypothetically, 3-hydroxy-3-methylglutaryl co-enzyme A (HMG-CoA) reductase inhibitors (statins) protect against arrhythmias in addition to their well-established secondary prevention benefits against atherosclerotic coronary artery disease. The use of statins has been suggested to protect against atrial fibrillation (AF) in some clinical studies, but remains rather inadequately explored… View more
Author(s): Peter M Nilsson Added: 3 years ago
Some cardiovascular (CV) risk-prone patients are easy to recognise, for example following manifestations of cardiovascular disease (CVD), coronary artery bypass graft (CABG) or percutaneous transluminal coronary angioplasty (PTCA) interventions, and they deserve appropriate risk-factor control for secondary prevention, including blood pressure (BP) lowering. However, many other at-risk patients… View more
Author(s): Michel Burnier Added: 3 years ago
In 2007, the European Society of Hypertension (ESH) and the European Society of Cardiology (ESC) published their guidelines for the management of arterial hypertension.1 These guidelines covered in detail all aspects of the management of hypertensive patients, from the diagnosis and detection of early subclinical organ damage to the discussion of the various therapeutic strategies in essential… View more
Author(s): Roland E Schmieder Added: 3 years ago
It is widely acknowledged that effective management of hypertension – even if blood pressure (BP) is reduced by only 2mmHg – can significantly reduce the incidence of stroke, myocardial infarction (MI) and heart failure (HF).1 However, despite the wide range of conventional antihypertensive agents available, approximately 70% of patients fail to achieve adequate BP control.2 Furthermore, although… View more