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Author(s): Lazar Mandinov , Federico M Asch , Eberhard Grube Added: 3 years ago
Functional mitral regurgitation (FMR) in patients with chronic myocardial ischaemia/infarction or dilated cardiomyopathy results from significant left ventricular remodelling with papillary muscle displacement and restrictive leaflet motion.1,2 Almost invariably, the mitral annulus is dilated and deformed, whereas the valve leaflets are morphologically normal. Surgically, annular reduction can be… View more
Author(s): Antonio Popolo Rubbio Added: 1 year ago
In this short video, Dr Antonio Popolo Rubbio (IRCCS Policlinico San Donato, IT) shares the key findings from a study that assessed the use of the MitraClip in patients with atrial functional mitral regurgitation. Discussion Points 1. Study Background 2. Mitraclip Procedure 3. Study Design & the Patient Selection Criteria 4. Key Findings 5. Which Patients Would Benefit the Most from this… View more
Author(s): Lutz Buellesfeld , Lazar Mandinov , Eberhard Grube Added: 3 years ago
Mitral regurgitation (MR) is a complex haemodynamic abnormality of various aetiologies that may lead to heart failure and sudden cardiac death.1–3 The prevalence of MR in unselected populations increases with age, from less than 10% among individuals under 40 years of age to approximately 33% among those over 70 years of age.2,4 Most instances of MR found in the general middle-aged population are… View more
Author(s): David Messika-Zeitoun , Jean-Michel Serfaty , Dominique Himbert , et al Added: 3 years ago
Functional mitral regurgitation is a regurgitation that occurs despite a structurally normal mitral valve as a consequence of left ventricular dysfunction. It is a common feature of both dilated and ischaemic cardiomyopathy, and the presence and degree of severity of mitral regurgitation is associated with an increased risk of death and congestive heart failure.1–3 Mechanisms leading to… View more
Author(s): Martin Swaans , Ben van den Branden , Marco Post , et al Added: 3 years ago
In Europe, mitral regurgitation (MR) is the second most common form of valvular heart disease needing surgery.1 Studies have shown that up to 50 % of patients with severe symptomatic MR are not referred to surgery, even if a surgical indication exists.1–3 Reasons for denying surgery include impaired left ventricular ejection fraction, a high operative risk, multiple comorbidities or advanced age… View more
Author(s): Michele De Bonis , Ottavio Alfieri Added: 3 years ago
Degenerative mitral regurgitation (MR) represents a rather common pathology, affecting 1–2% of the general population. In patients requiring surgery for this disease, mitral valve repair is the standard of care. Whenever feasible it is preferable to prosthetic replacement, as it provides better preservation of left ventricular (LV) function, higher survival, lower rates of thromboembolism and… View more
Author(s): Eduardo Alegria-Barrero , Olaf W Franzen Added: 3 years ago
Diseases of the mitral valve (MV) are the second most frequent clinically significant form of valvular disease in adults. In particular, MV regurgitation occurs with increasing frequency as part of degenerative changes in the ageing process.1 The annual incidence of degenerative MV disease is estimated at approximately 2–3 %. In addition to degenerative valve disease, MV regurgitation can be… View more
Author(s): Stephan Baldus Added: 1 year ago
Prof Stephan Baldus (University of Köln Medical Center, DE) shares insights from the TriCLASP post-market study (NCT04614402). This postmarket clinical follow up study, presented at EuroPCR 2022, assessed the safety and effectiveness of the Edwards PASCAL Transcatheter Valve Repair System in transcatheter tricuspid valve repair. Discussion Points: 1. Unmet needs of patients with TR 2. Study… View more