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Author(s): Nazzareno Galiè Added: 3 years ago
The field of pulmonary arterial hypertension (PAH) has recently been characterised by rapid improvements in therapeutic options and corresponding improvements in patient outcomes. In 1991, estimates from the US Department of Health and Human Services National Institutes of Health (NIH) Registry painted a grim portrait of survival in patients with pulmonary hypertension - then called primary… View more

Vascular Disease and Surgery

Prevention & Chronic Conditions
Author(s): Arturo Evangelista Added: 3 years ago
The International Registry of Acute Aortic Dissection (IRAD) was established in 1996, enrolling patients at large referral centres worldwide. It represents a unique opportunity to assess the current presentation, management and outcome of acute aortic syndrome (AAS). The IRAD is an observational registry with more than 1,500 patients enrolled at 21 tertiary centres in six countries. Collected… View more

Prevention & Chronic Conditions
Author(s): Silvia Ulrich Added: 3 years ago
Structural and functional changes in the vascular wall and thrombus formation are the main factors responsible for increased pulmonary vascular resistance in patients with pulmonary hypertension (PH).1,2 The contribution of each of these factors is thought to be different among the variable underlying causes of PH, thereby accounting for varying response to vasodilatative and antiproliferative… View more

Prevention & Chronic Conditions
Author(s): Christoph Maack , Michael Böhm Added: 3 years ago
Chronic heart failure is the leading cause of hospitalisation in Germany1 and other European countries. It is the result of various cardiovascular diseases, such as myocardial infarction, arterial hypertension and valvular heart diseases. About 50 % of patients with heart failure have normal systolic, but impaired diastolic function, a condition termed heart failure with preserved ejection… View more

Heart Failure

Prevention & Chronic Conditions
Author(s): Carsten Schwenke , Monica Boos , Rainer Hentrich , et al Added: 3 years ago
Since its introduction in 1993,1 contrast-enhanced magnetic resonance angiography (ce-MRA) has been considered the technique of choice for angiographic examination of most regions of the body. This is because of several technical and clinical advantages in comparison with non-contrast-enhanced MRA (nce-MRA) imaging. In this article, we focus on patients with suspected peripheral arterial… View more

Imaging & Diagnostics
Palpitations in the Cancer Patient
Author(s): Hani Essa , Gregory YH Lip Added: 2 years ago

Electrophysiology & Arrhythmia

CV Disease in Special Populations
TCT 2018: Prosthesis-Patient Mismatch
Author(s): Howard C Herrmann Added: 5 years ago
Prof Howard C. Hermann (University of Pennsylvania, US) discusses prosthesis-patient mismatch - Incidence, predictors and outcome of prosthesis-patient mismatch after transcatheter aortic valve replacement. Filmed by Radcliffe Cardiology on site TCT 2018. View more

Vascular Disease and Surgery

Intervention
Author(s): Carmine Dario Vizza , Roberto Badagliacca , Roberto Poscia , et al Added: 3 years ago
Abstract Pulmonary arterial hypertension (PAH) is a serious and life-threatening condition for which the prognosis remains poor. Treatment options include endothelial receptor antagonists, phosphodiesterase (PDE5) inhibitors and prostanoids. Despite all demonstrating good short-term efficacy, none of the currently available drug therapies are curative. Treatment with prostanoids is complex and… View more

Electrophysiology & Arrhythmia

Prevention & Chronic Conditions
Author(s): Diego Penela , Maríbel Diaz-Ricart , Magda Heras Added: 3 years ago
The usual underlying mechanism of acute coronary syndromes (ACSs) is a thrombotic event caused by the rupture or erosion of an atherosclerotic plaque. In this scenario, platelets and thrombin are key players. Thus, understanding the physiopathology of platelet activation is of paramount importance in the treatment of acute coronary ischaemia. There is ample evidence showing that adequate… View more

Anticoagulation

MI/ACS
Author(s): Sitaramesh Emani , William T Abraham Added: 3 years ago
Heart failure (HF) is a growing epidemiological challenge in the US and worldwide. In the US, it is estimated that at least 5 million people are affected by it, with more than a half-million new diagnosis being made each year.1 Despite major improvements in the treatment of HF, almost 30 % of patients treated for acute HF require readmission within 30 days.2,3 These sobering statistics underscore… View more

Heart Failure

Prevention & Chronic Conditions