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Author(s): Carmela Nappi , Valeria Gaudieri , Alberto Cuocolo Added: 3 years ago
Evaluating stress-induced myocardial perfusion defects by non-invasive myocardial perfusion imaging (MPI) modalities has taken a leading role in the identification of flow-limiting epicardial coronary artery disease (CAD); it has excellent diagnostic and prognostic value. Non-invasive MPI can be performed using conventional and novel gamma cameras or PET/CT.1 A range of imaging techniques has… View more

Imaging & Diagnostics

Prevention & Chronic Conditions
Author(s): Jyrki T Kuikka Added: 3 years ago
Myocardial perfusion imaging (MPI) using combined computed tomography (CT) and single-photon emission CT (SPECT) systems plays an important role in the management of patients with coronary artery disease (CAD).1–4 The method can be used to assess myocardial perfusion and left ventricular function simultaneously. It is an especially valuable tool for assessing short-term risk of CAD, thus… View more

Imaging & Diagnostics
Author(s): W Kevin Tsai , Kathleen M Holohan , Kim Allan Williams Added: 3 years ago
Coronary artery disease (CAD) represents a tremendous financial and health burden as the leading cause of death in the US.1 Acute coronary syndrome and its subsequent manifestations, including heart failure and need for cardiac transplantation, are associated with significant morbidity and mortality. Hypertension, dyslipidemia, tobacco abuse, diabetes, chronic kidney disease, and family history… View more

Imaging & Diagnostics

Prevention & Chronic Conditions
Author(s): Mario Petretta , Carmela Nappi , Alberto Cuocolo Added: 3 years ago
The application of nuclear medicine techniques to cardiology is based on the identification of the functional consequences of coronary stenoses, i.e. of myocardial ischaemia. In nuclear cardiology, the evaluation of myocardial perfusion with single-photon-emission computed tomography (SPECT) is the most commonly performed procedure. The SPECT study is currently performed with electrocardiogram … View more

Imaging & Diagnostics
Author(s): Maria Grazia Modena , Annachiara Nuzzo , Rosario Rossi , et al Added: 3 years ago
Women with angina but no obstructive coronary artery disease (CAD) at coronary angiography have long been considered a low-risk population.1–3 Instead, data from the Women‘s ischaemia syndrome evaluation (WISE) study4 demonstrated that persistent chest pain (PChP) – also in the absence of CAD – is not a benign condition. These patients experienced major cardiovascular (CV) events, such as… View more

Demographic
Author(s): Mai Tone Lønnebakken , Eva Gerdts Added: 3 years ago
Coronary artery disease (CAD) remains a diagnostic challenge, even though there are several diagnostic techniques available for the detection of ischaemia – assessed either as function or perfusion abnormalities or directly by demonstrating anatomical coronary stenoses.1 An overview of different non-invasive modalities used in the diagnosis of myocardial ischaemia and their average sensitivity… View more

Imaging & Diagnostics

Prevention & Chronic Conditions
Author(s): Santo Dellegrottaglie , Pierluigi Costanzo , Stefania Paolillo , et al Added: 3 years ago
In Europe, subjects >65 years of age currently constitute 17% of the entire population, with some variations between countries (see Figure 1).1 More importantly, as a consequence of the ageing population, elderly subjects are expected to account for 30% of the European population by 2050. Currently, cardiovascular disease is the major cause of death in Europe (~20% of all causes) and more than… View more

Imaging & Diagnostics
Author(s): Andreas H Mahnken Added: 3 years ago
Over the last few decades, the rapid development of cardiac computed tomography (CT) has been unequalled by any other imaging technique. The driving forces behind cardiac multidetector-row CT (MDCT) are the enormous socioeconomic relevance of coronary artery disease (CAD) and the need for comprehensive, reliable and reproducible diagnostic tests that overcome the morbidity and mortality of… View more

Imaging & Diagnostics

Heart Failure
Author(s): Covadonga Fernández-Golfín , Jose Luis Zamorano Added: 3 years ago
Since the introduction in the early 1980s of magnetic resonance imaging (MRI) in clinical practice, contrast agents (CAs) have been part of MR studies enhancing the capabilities of this diagnostic technique. CAs enhance the contrast between different types of tissues. Tissue contrast depends largely on proton concentration and longitudinal (T1) and transversal (T2) relaxation times inherent to… View more

Imaging & Diagnostics
Author(s): Todd D Miller , J Wells Askew Added: 3 years ago
Case Study A 47-year-old male truck driver with no previous history of heart disease presents for his annual Department of Transportation physical. He has noticed mild dyspnoea when climbing stairs but not with other activities of daily living. He denies chest discomfort, palpitations, orthopnoea, paroxysmal nocturnal dyspnoea or ankle oedema. His risk factors for coronary artery disease (CAD)… View more

Imaging & Diagnostics

Electrophysiology & Arrhythmia