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Author(s): Antoni Martínez-Rubio , Soledad Ascoeta , Fadwa Taibi , et al Added: 3 years ago
In the last months of 2019 and the beginning of 2020, a novel disease appeared, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a very contagious virus, which causes coronavirus disease 2019 (COVID-19). The clinical manifestations of this virus in humans vary widely from asymptomatic to severe, with diverse symptomatology and even death. The substantial transmission from… View more
Author(s): Vincent Floré , Rik Willems Added: 3 years ago
Sudden cardiac arrest (SCA) can be defined as the abrupt cessation of cardiac activity due to an underlying cardiac cause, occurring instantaneously in a previously stable patient and in the absence of non-cardiovascular causes (e.g., trauma, intoxication, drowning, electrocution).1,2 SCA will lead to loss of consciousness within the minute due to insufficient cerebral perfusion. If no immediate… View more
Author(s): Frank Grothues Added: 3 years ago
Cardiovascular magnetic resonance (CMR) imaging, with its versatility and ability for soft tissue characterisation in conjunction with the lack of ionising radiation, has over the past decade evolved as a first-line imaging tool for several diagnostic problems.1 Developments in this field, especially the introduction of the ‘late enhancement’ (LE) imaging technique by the working group of Kim and… View more
Author(s): Dennis V Cokkinos , Christos Belogianneas Added: 3 years ago
The term cardiac remodelling (REM) is used to define changes that produce geometrical rearrangement of the normal structures of the heart, together with complex biological and molecular alterations. REM affects the heart at the level of the cardiomyocyte, the blood vessels and the extracellular matrix. Proliferation of the latter, resulting in fibrosis, is one of the hallmarks of pathological REM… View more
Author(s): Ricardo A Perez de la Hoz , Sandra Patricia Swieszkowski , Federico Matias Cintora , et al Added: 3 years ago
The aim of reviewing the neuroendocrine–humoral response in acute coronary syndrome (ACS) is based on the fact that beyond the distinctive thrombotic event that defines acute occlusion of a coronary artery, generically referred to as a plaque accident, it is not an isolated event. It is clear that a series of physiological and physiopathological mechanisms related to stress – before, during and… View more
Author(s): Daniel Alejandro Lerman , Nasri Alotti , Kiddy Levente Ume , et al Added: 3 years ago
Acute myocardial infarction (AMI) is still a major public health problem worldwide, causing high rates of morbidity and mortality. In the United States, nearly one million patients suffer from AMI each year.1 In the UK, around 80,000 people died from coronary heart disease (CHD) in 2010.2 The current approach to the treatment of myocardial infarction involves early revascularisation with… View more
Author(s): Antonio J Vallejo-Vaz Added: 3 years ago
Heart Failure – A Major Global Health Problem Cardiovascular diseases (CVDs) remain the leading cause of morbidity and mortality in developed countries and its burden is progressively increasing.1–4 Coronary artery disease (CAD) and other conditions, such as hypertensive heart disease or diabetes mellitus, are rated among the foremost reasons for morbi-mortality worldwide.1–4 In this context,… View more