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3 years ago
Myocardial infarction (MI) is associated with acute risk of early malignant arrhythmias that can be easily treated during in-hospital intensive care by defibrillation, adjuvant antiarrhythmic therapy or even catheter ablation in resistant cases. Indeed, such management resulted in substantial improvement in MI survival rate. Despite the implementation of primary percutaneous coronary…
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3 years ago
Despite considerable improvements in the treatment of acute ST elevation myocardial infarction (STEMI), outcomes have predominantly improved in STEMI patients without cardiogenic shock (CS). Nevertheless, cardiogenic shock occurs in approximately 7–10% of STEMI patients and is the leading cause of death for hospitalised patients. In-hospital mortality rates of STEMI complicated by CS are around…
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3 years ago
Cardiogenic shock is the leading cause of death in patients with acute ST-elevation myocardial infarction (STEMI). Characterised by a state of low cardiac output leading to end-organ hypoperfusion, cardiogenic shock complicates approximately 5–8 % of STEMIs and is associated with a mortality rate approaching 50 percent.1–3 Prompt recognition and therapeutic intervention for cardiogenic shock due…
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3 years ago
The cumulative evidence base informing almost every aspect of myocardial infarction acute coronary syndrome (ACS) care is expansive and has been associated with a decline in the rate of mortality. Within the context of current-era clinical trials of ST-segment-elevation myocardial infarction, 30-day mortality rates of 4–5% have now been reported for high-risk individuals,1,2 with similar rates…
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3 years ago
In the setting of acute myocardial infarction (AMI), spontaneous and percutaneous coronary intervention (PCI)-related embolisation results in a decreased efficacy of mechanical reperfusion and myocardial salvage. Direct stenting without predilation may decrease embolisation and the incidence of the no-reflow phenomenon.1,2 More specific approaches to the problem of microvessel embolisation during…
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3 years ago
Background: Coronary artery disease (CAD) and its major manifestation acute MI (AMI) are the most common causes of death worldwide. Hyperhomocysteinemia (HHcy) has been recently recognised as a new emerging cardiovascular risk factor mediating in development of CAD risk. HHcy causes endothelial dysfunction, resulting in local thrombosis and subsequent ischaemia. However, the role of HHcy in…
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Abortion of Acute Myocardial Infarction - The Best Possible Achievement of Reperfusion Therapy
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3 years ago
Article
Added:
3 years ago
Acute myocardial infarction (AMI) is a major cause of morbidity and mortality worldwide. Accordingly, prompt identification of patients with AMI is critical, as established therapies exist that are of proven benefit.1,2 More than 15 million patients per year present to emergency departments with symptoms compatible with acute myocardial ischaemia in the US and Europe; only 20–30%, however, are…
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Added:
6 years ago
This interview with Robin Hofmann from Karolinska Institutet, Stockholm, SE discusses Determination of the Role of Oxygen in Suspected Acute Myocardial Infarction (DETOX) at ESC 2017.
Filmed by Radcliffe Cardiology on-site .
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Added:
3 years ago
Early coronary angiography performed during acute MI (AMI) identifies an occluded vessel in most patients with ST elevation MI (STEMI)1 and less frequently in those with non-STEMI;2 however, ≥90 % of patients with AMI have evidence of obstructive coronary artery disease.3 For these patients with overt coronary artery disease (CAD), the benefits of reperfusion strategies and cardioprotective…
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