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Author(s): Carlo Briguori , Antonio Colombo Added: 3 years ago
Patients with type 2 diabetes mellitus represent 25% of those requiring myocardial revascularisation.1 Although current guidelines favour coronary bypass surgery (CABG) over percutaneous coronary intervention (PCI) in most diabetics who require revascularisation, 2–3 substantial variability exists in practice patterns between individual hospitals, suggesting a lack of clinical consensus.4 The… View more

Prevention & Chronic Conditions

Intervention
Author(s): Lucy Blows , Simon Redwood Added: 3 years ago
Transforming a critically narrowed coronary vessel to one that is angiographically smooth and unobstructed is immensely satisfying. However, if the procedure is examined in its component parts, it is surprising that this technique is considered safe with minimal overt clinical complications. Temporary vessel occlusion renders the downstream myocardium ischaemic, while vessel trauma initiates… View more

Intervention
Cardiac Disease after Pregnancy: A Growing Problem
Author(s): Christina Y Aye , Henry Boardman , Paul Leeson Added: 3 years ago
Historically pregnancy has been viewed as only clinically relevant to women and for the relatively brief time from conception to the puerperium. However it is now clear that events during pregnancy have much longer-term implications, particularly for cardiovascular health, both for the mother and her offspring. Pregnancy complications such as hypertension and preterm birth appear to serve as a… View more

Demographic
Author(s): Lucy Blows , Simon Redwood Added: 3 years ago
Transforming a critically narrowed coronary vessel to one that is angiographically smooth and unobstructed is immensely satisfying. However, if the procedure is examined in its component parts, it is surprising that this technique is considered safe with minimal overt clinical complications. Temporary vessel occlusion renders the downstream myocardium ischaemic, while vessel trauma initiates… View more

Prevention & Chronic Conditions
Author(s): Jean-Pierre Laissy , Jérôme Garot Added: 3 years ago
Recent developments in cardiac magnetic resonance (CMR) imaging have led to a tremendous breakthrough in functional imaging and tissue characterisation of the left ventricular (LV) myocardium. Over the past few decades, numerous studies have shown significant improvement in CMR imaging of acute myocardial ischaemia and myocardial infarction (MI). Advances in hardware, acquisition sequences and… View more

Imaging & Diagnostics
What is the Real Message of the ISCHEMIA Trial from a Clinician’s Perspective?
Author(s): Islam Y Elgendy , Carl J Pepine Added: 3 years ago
Management goals in patients with stable coronary disease or chronic coronary syndrome include controlling symptoms and reducing the risk of future cardiovascular events.1,2 Randomised trials conducted in the bare metal stents era have indicated that an invasive management strategy, which includes coronary angiography, followed by percutaneous or surgical revascularisation, if indicated, was not… View more

Prevention & Chronic Conditions
Author(s): Juan Carlos Kaski , Hiroaki Shimokawa Added: 7 months ago

Vascular Disease and Surgery

Prevention & Chronic Conditions
Author(s): Denise Hilfiker-Kleiner , Gerald S Werner , Gerd Heusch Added: 3 years ago
A Cathepsin D-Cleaved 16kDa Form of Prolactin Mediates Postpartum Cardiomyopathy Hilfiker-Kleiner D, Kaminski K, Podewski E, et al. Cell, 2007;128(3):589–600 Postpartum cardiomyopathy (PPCM) is a disease of unknown aetiology exposing women to high risk of mortality after delivery. This study shows that female mice with a cardiomyocyte-specific deletion of STAT3 develop PPCM. In these mice,… View more

Heart Failure
Cardiac Involvement Due to COVID-19
Author(s): Valentina O Puntmann , Anastasia Shchendrygina , Carlos Rodriguez Bolanos , et al Added: 6 months ago

Imaging & Diagnostics

COVID-19
Author(s): Kensuke Nishimiya , Yasuharu Matsumoto , Hiroaki Shimokawa Added: 3 years ago
Vasa Vasorum The coronary arterial wall generally consists of the tunica intima, tunica media and tunica adventitia. In particular, the coronary adventitia harbours the vasa vasorum (VV),which has a diameter of 50–300 μm and plays an important role as a network of nutrient blood vessels to the arterial wall (Figure 1).1–3 The VV is enhanced in association with arterial wall thickening when the… View more

Imaging & Diagnostics