Search results
Added:
3 years ago
Dr Shao Hui (University of Florida, Florida, US) discusses the rationale and methods behind a Bayesian interpretation on whether intensive glycaemic control can reduce major adverse cardiovascular events (MACE) using data in long-term clinical trials (e.g. ACCORD and VADT).
Questions:
1. What is the rationale behind this analysis?
2. What were the methods of this analysis?
3. What were your…
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Added:
3 years ago
Aim: New antidiabetic drugs are required to be evaluated in cardiovascular outcome trials (CVOTs). Few of these are direct comparisons between new drugs, so we performed a network meta-analysis to compare the new drug classes in terms of cardiovascular outcomes.
Method: We searched for CVOTs involving glucagon-like peptide-1 receptor agonists (GLP-1 RAs), sodium-glucose co-transporter 2 (SGLT-2)…
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Added:
3 years ago
Aim: Lowering systolic blood pressure (SBP) to <120 mmHg has been shown to reduce cardiovascular events and mortality. Whether this should be the target is controversial. We therefore studied the relationship between SBP attained and outcome using network meta-analysis.
Methods: We searched for randomised trials comparing different SBP targets. The mean SBP attained was classified into five…
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5 months ago
Added:
7 months ago
ESC 2023 — Dr Ziad Ali (DeMatteis St Francis, US) joins us to discuss the findings from the ILUMIEN IV clinical trial (NCT03507777).
ILUMIEN IV (Abbott Medical Devices)is a prospective, single-blind clinical trial aiming to compare optical coherence tomography (OCT) to an angiography-guided stent implantation strategy. The trial investigated which method achieved a larger post-percutaneous…
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Platelet Function Testing in Clinical Practice - Experience and Views from Europe and the US
Added:
3 years ago
Article
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2 years ago
In this short interview, Dr Rafael Romaguera (University of Barcelona, SP) discusses the findings from the SUGAR trial.This randomized head-to-head trial aimed to compare Cre8 EVO stents to a contemporary drug-eluting stent (DES) in patients with diabetes (DM) and coronary artery disease. The trial, first presented at TCT 2021, demonstrated that Cre8 EVO stents were non-inferior to Resolute Onyx…
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Added:
5 months ago
AHA 2023 — Investigator, Dr Steven E Nissen (Cleveland Clinic, US) is interviewed by CardioNerds Medical Education Fellow, Dr Maryam Barkhordarian (HMH Palisades Medical Center, US) on the trial that assessed the efficacy and safety of lepodisiran, a small interfering RNA (NCT05565742).The main purpose of this phase 2, randomised, double-blind, placebo-controlled study (Eli Lilly and Company) is…
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Added:
1 week ago
ACC.24 — Dr Alexander Fanaroff (Penn Medicine, US) joins us onsite at ACC.24 to discuss the findings from the BE ACTIVE study, which investigated behavioural economic approaches to increasing physical activity (PA) in patients with an elevated risk of cardiovascular disease (NCT03911141).This randomized, controlled trial enrolled 1062 patients with a 10-year atherosclerotic cardiovascular risk…
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Added:
2 years ago
