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Author(s): Sophie Mavrogeni , George Markousis-Mavrogenis , Genovefa Kolovou Added: 3 years ago
Systemic means ‘pertaining to or affecting the whole body’ as opposed to a localised condition. A systemic disease is one that affects a number of organs and tissues, or the body as a whole. Systemic diseases, according to WHO classification,1 and cardiac diseases that developed during their course, are listed in Table 1. Download original Thyroid diseases, pheochromocytoma and growth hormone… View more

Imaging & Diagnostics

Heart Failure
Author(s): Douglas Ewan Cannie , Mohammed Majid Akhtar , Perry Elliott Added: 3 years ago
Heart failure is a global health challenge, affecting 1–2% of the population and up to an estimated 64 million people worldwide.1,2 In the UK, just under 1 million people have heart failure, with approximately 350 new diagnoses each year per 100,000 population.3 The lifetime risk of developing heart failure at 55 years of age is 33% for men and 28% for women.4 The heart failure population is… View more

Heart Failure
Author(s): Peter P Swoboda , Adam K McDiarmid , Stephen P Page , et al Added: 3 years ago
Inherited cardiomyopathies are primary disorders of the heart muscle that have a genetic basis. On long-term follow-up they are associated with adverse outcomes, particularly sudden death, arrhythmia and heart failure.1 The diagnosis is made on the basis of clinical, cardiac imaging (primarily with transthoracic echocardiography) and genetic features,2 ideally by a tertiary inherited cardiac… View more

Imaging & Diagnostics

Heart Failure
Author(s): Gianfranco Sinagra , Michele Moretti , Giancarlo Vitrella , et al Added: 3 years ago
According to the latest position statement of the European Society of Cardiology (ESC), cardiomyopathies (CMP) are defined as “myocardial disorders in which the heart muscle is structurally and functionally abnormal, in the absence of coronary artery disease, hypertension, valvular disease and congenital heart disease sufficient to cause the observed myocardial abnormality”.1 CMP may be… View more

Imaging & Diagnostics

Heart Failure
Management of HF in Patients with CKD
Author(s): David K Ryan , Debasish Banerjee , Fadi Jouhra Added: 1 year ago

Heart Failure

Prevention & Chronic Conditions
Author(s): Andrew K Roy , John Keaney , Niall G Mahon , et al Added: 3 years ago
The coexistence of heart and kidney disease represents an evolving epidemic in an ageing population, with chronic kidney disease (CKD) incidence rates increasing annually.1 The effect of dysfunction of one kidney mediates profound effects on the other, recently described and defined as five distinctive cardiorenal subtypes by the Acute Dialysis Quality Initiative consensus group.2 Much work has… View more

MI/ACS
Cardiovascular Complications of Chronic Kidney Disease: An Introduction
Author(s): Hilary Warrens , Debasish Banerjee , Charles A Herzog Added: 1 year ago

Prevention & Chronic Conditions

CV Disease in Special Populations
ESC 23: The HEART-FID Study
Author(s): Robert Mentz Added: 7 months ago
ESC 2023 — Dr Robert Mentz (Duke University Medical Center, US) joins us to provide a succinct summary of the findings and key take-home messages from the HEART-FID study (NCT03037931). HEART-FID(American Regent, Inc.) aimed to determine the safety and efficacy of iron therapy using intravenous (IV) ferric carboxymaltose (FCM) as compared to a placebo in the treatment of patients with heart… View more

Heart Failure
Author(s): Kana Shimizu , Masafumi Funamoto , Mai Genpei , et al Added: 3 years ago
Topic: 3. Heart Failure and Cardiomyopathy Introduction and Objectives Signals activated by increased hemodynamic overload to the heart finally reach the nuclei of cardiac myocytes and induce maladaptive hypertrophy in them. Nuclear acetylation, which is controlled by histone deacetylases and the intrinsic histone acetyltransferase p300, is a critical event in this process. We previously… View more

Heart Failure
The Natural Product Zerumbone Suppresses Pressure Overload-Induced Cardiac Dysfunction by Inhibiting Cardiac Hypertrophy and Fibrosis
Author(s): Mikuto Tojima , Yasufumi Katanasaka , Yoichi Sunagawa , et al Added: 2 years ago

Prevention & Chronic Conditions