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Author(s): José PS Henriques Added: 3 years ago
Despite considerable improvements in the treatment of acute ST elevation myocardial infarction (STEMI), outcomes have predominantly improved in STEMI patients without cardiogenic shock (CS). Nevertheless, cardiogenic shock occurs in approximately 7–10% of STEMI patients and is the leading cause of death for hospitalised patients. In-hospital mortality rates of STEMI complicated by CS are around… View more

MI/ACS
Author(s): Ricardo Seabra-Gomes , Jorge Ferreira Added: 3 years ago
Cardiogenic shock (CS) is a state of systemic tissue hypoperfusion due to cardiac failure in the presence of adequate intravascular volume.1 Left ventricular pump failure leading to CS remains one of the most serious and challenging conditions over time in cardiology and is still the most common cause of hospital mortality associated with myocardial infarction (MI).2 This review focuses on CS in… View more

Prevention & Chronic Conditions

MI/ACS
Author(s): Lee Chang , Robert Yeh Added: 3 years ago
Cardiogenic shock is the leading cause of death in patients with acute ST-elevation myocardial infarction (STEMI). Characterised by a state of low cardiac output leading to end-organ hypoperfusion, cardiogenic shock complicates approximately 5–8 % of STEMIs and is associated with a mortality rate approaching 50 percent.1–3 Prompt recognition and therapeutic intervention for cardiogenic shock due… View more

Vascular Disease and Surgery

Prevention & Chronic Conditions
Author(s): Dominik Wiedemann , Thomas Haberl , Julia Riebandt , et al Added: 3 years ago
History of Mechanical Circulatory Support The first reported clinical use of a left ventricular assist device (LVAD) was by Liotta and Crawford in 1963. Via a left thoracotomy, an intracorporeal pneumatically driven pump was implanted using left atrial inflow and descending thoracic aortic outflow. Despite the successful implantation, the patient died within a short period of time after the… View more

Vascular Disease and Surgery

Imaging & Diagnostics
Novel Aspects of Classification, Prognosis and Therapy in Takotsubo Syndrome
Author(s): Chiara Di Filippo , Beatrice Bacchi , Carlo Di Mario Added: 3 years ago
Takotsubo syndrome (TTS) is a transient form of acute heart failure that mimics an acute coronary syndrome (ACS), with comparable acute adverse outcome.1 Many hypotheses have been formulated, but the pathophysiology of TTS is still not fully understood. Recently, it was demonstrated that specific alterations in neurological response and sympathetic activation after emotional stimuli are present… View more

Heart Failure
Cutting Balloon Versus Conventional Balloon Angioplasty for the Treatment of Coronary Artery Disease
Author(s): Remo Albiero Added: 3 years ago
The cutting balloon (CB)1 is a special balloon catheter with three or four atherotomes (microsurgical blades) bonded longitudinally to its surface, suitable for creating discrete longitudinal incisions in the atherosclerotic target coronary segment during balloon inflation. With the cutting balloon, the increase in the vessel lumen diameter is obtained in a more controlled fashion and with a… View more

Prevention & Chronic Conditions
Author(s): Michael Hoebartner , Philipp Kiefer , Michael Andrew Borger , et al Added: 3 years ago
Mitral valve regurgitation (MR) is frequently induced by degenerative mitral valve (MV) disease and leads to leaflet prolapse. Therefore, valve repair is a well-proven surgical technique with excellent long-term outcomes.1–5 The risk of declining left ventricle (LV) function or LV enlargement and the development of atrial fibrillation or severe pulmonary hypertension due to chronic volume… View more

Intervention

Vascular Disease and Surgery
Author(s): Patricia Fonseca , Raphael Rosenhek , Vinayak Bapat , et al Added: 3 years ago
Degenerative aortic stenosis (AS) is a chronic progressive valvular disease that affects approximately 1.4 % of individuals over 65 years and 4.6 % of patients older than 75 years in the US.1 While the prognosis of asymptomatic patients with severe AS is generally good, that of symptomatic patients is very poor, with an overall mortality of approximately 80 % at three years once the disease… View more

Vascular Disease and Surgery

Intervention
ACC.24: The SMART Trial
Author(s): Howard C Herrmann Added: 1 week ago
ACC.24 — Investigator, Dr Howard C Hermann (Penn Medicine, Philadelphia, PA, US) joins us to discuss the findings from the SMART Trial (NCT04722250).This prospective, multi-center, randomized controlled study aims to investigate the valve safety and performance of self expanding as compared to balloon-expandable transcatheter aortic valve replacement (TAVR) in patients with small aortic annuli… View more

Intervention
Drug Release Profiles of Different Drug-coated Balloon Platforms
Author(s): Torsten Heilmann , Christian Richter , Heiko Noack , et al Added: 3 years ago
Drug-coated balloons (DCBs) are a nascent technology gaining a lot of attention among cardiologists and angiologists worldwide. As opposed to drug-eluting stents (DES) they allow intraluminal drug application to diseased arterial tissue without leaving an implant such as a metal scaffold behind. This may be beneficial where a stent is already in place or where stenting is problematic due to… View more

Intervention