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Advances in the Treatment of Pulmonary Arterial Hypertension
Author(s): Robert Voswinckel , Ralph T Schermuly , Norbert Weissmann , et al Added: 3 years ago
Pulmonary arterial hypertension (PAH) is a chronic, progressive disease defined by increasing pulmonary vascular resistance and pulmonary arterial pressure, ultimately leading to right heart failure. The life expectancy of patients with PAH who do not receive appropriate treatment is dramatically reduced. Guidelines for the diagnosis and treatment of PAH have been established by the American… View more

Prevention & Chronic Conditions
Circulating Biomarkers in Lower Extremity Artery Disease
Author(s): Louise Ziegler , Ulf Hedin , Anders Gottsäter Added: 2 years ago

Vascular Disease and Surgery
Research Area(s) / Expertise: Job title: Professor of Medicine
Dr Martin B. Leon is a prominent figure in the field of interventional cardiovascular medicine, contributing significantly to the industry. Currently serving as the Professor of Medicine at Columbia University Irving Medical Center, he has held key roles such as the Director of the Columbia Interventional Cardiovascular Care and, until July 2023, Director of the Cardiovascular Data Science Center… View more
Author(s): Esha Sachdev , C Noel Bairey Merz , Puja K Mehta Added: 3 years ago
Takotsubo cardiomyopathy (TTC) has gained more recognition since its first description in 1990 by Satoh et al.1,2 The word takotsubo refers to the Japanese octopus trapping pot with a large round base and narrow neck, which is the characteristic shape of the left ventricle (LV) in this syndrome, although other morphologies have since been described.3 TTC is known by many names including stress… View more

Heart Failure

Prevention & Chronic Conditions
Author(s): Claudio Borghi , Arrigo FG Cicero Added: 3 years ago
It is well known that hypertension is a strong independent risk factor for coronary and cerebrovascular diseases, as well as for heart failure, atrial fibrillation and chronic renal failure, in both industrialised and developing countries,1 thus substantially contributing to the global burden of disease. Moreover, it is well known that reducing blood pressure (BP) in hypertensive patients is… View more

Prevention & Chronic Conditions
Anticoagulant Therapy for Patients with Coronavirus Disease 2019: Urgent Need for Enhanced Awareness
Author(s): Maki Komiyama , Koji Hasegawa Added: 3 years ago
Coronavirus disease 2019 (COVID-19), which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has generated a pandemic that has heavily affected the global population, with more than 5.2 million infected and more than 337,000 deaths worldwide recorded between the end of 2019 and 24 May 2020.1 In the absence of vaccines or specific targeted treatments, strategies to… View more

COVID-19
Author(s): Daniel Alejandro Lerman , Sai Prasad , Nasri Alotti Added: 3 years ago
Progressive thickening of the aortic valve leaflets and narrowing of the aortic annulus leads to increased mechanical stress on the left ventricle and reduces cardiac output, resulting in further complications.1–3 The proportion of the population affected increases as the median age of a country or region rises. Approximately 2–4 % of people aged over 65 will develop calcific aortic stenosis,… View more

Vascular Disease and Surgery

Intervention
William Fearon
Job title: Professor of Medicine, Director of Interventional Cardiology
Dr William Fuller Fearon is a Professor of Medicine and the Director of Interventional Cardiology at Stanford University School of Medicine.Dr Fearon graduated from Dartmouth College with his Bachelor’s in 1990. In 1994, he received his medical degree from Columbia University College of Physicians and Surgeons, where he was elected into the Alpha Omega Alpha Medical Honor Society.He completed an… View more
Author(s): Helen O'Brien , Rose Anne Kenny Added: 3 years ago
One of the greatest achievements of public health in the twentieth century has been the almost doubling of life expectancy in the Western world. Yet this now ageing population brings new challenges, as the prevalence of little-understood geriatric conditions increases, together with the rising prevalence of age-related disorders, such as syncope. The definition of syncope, as outlined by the… View more

Imaging & Diagnostics

Electrophysiology & Arrhythmia
Author(s): John G Coghlan Added: 3 years ago
The pace of progress in the field of pulmonary arterial hypertension (PAH) continues to be breathtaking. In the past couple of years two new oral agents have been granted licences. Fourteen major international drug trials are underway, many evaluating the role of combination therapies, and at least three agents (simvastatin, imatinib and aviptadil) are undergoing proof of concept studies in… View more

Prevention & Chronic Conditions