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Author(s): Petros Kikas , George Chalikias , Dimitrios Tziakas Added: 3 years ago
Sphingolipids are one of the major categories of lipids and beyond their role as structural membrane components they have important functions as signalling molecules in a wide array of biological processes. They are composed of two key lipid building blocks – long-chain bases (usually sphingosine or 1,3-dihydroxy-2-amino-4-octadecene) and fatty acids – and use a glycerol-based backbone to which… View more
Author(s): Gurushankar Govindarajan , James R Sowers , Craig S Stump Added: 3 years ago
There has been an increase in the prevalence of diabetes mellitus over the past 40 years, both in the US and worldwide. The worldwide prevalence of diabetes in 2000 was approximately 2.8% and is estimated to grow to 4.4% by 2030. This translates to a projected rise of diabetes from 171 million in 2000 to well over 350 million in 2030. The epidemic of diabetes will continue to rise as there is… View more
Author(s): Peter Libby Added: 3 years ago
In the Cardiology Masters section of European Cardiology Review, we bring you an insight into the career of a key contributor to the field of cardiology. In this edition, we feature Dr Peter Libby, Mallinckrodt Professor of Medicine, Harvard Medical School; and Cardiovascular Specialist, Brigham and Women’s Hospital. From Berkeley to Boston As the founding chairman of the department of… View more
Author(s): Maki Komiyama , Koji Hasegawa Added: 3 years ago
The novel coronavirus disease 2019 (COVID-19) first occurred in December 2019 in Wuhan, Hubei Province, China, and has already evolved into a rapidly expanding pandemic. The WHO has declared COVID-19, which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), to be a public health emergency of international concern.1 Until effective therapeutics and vaccines become available… View more
Author(s): Roland Asmar Added: 3 years ago
The greatest burden of cardiovascular disease (CVD) is due to non-fatal morbidity and its consequences; whereas CVD accounts for approximately 17 million deaths each year worldwide, current estimates indicate that CVD associated with asymptomatic disease and target organ damage as a result of undetected cardiovascular risk factors affects 128 million people worldwide.1,2 Moreover, the worldwide… View more
Author(s): Marianne Yngen Added: 3 years ago
Introduction Diabetes mellitus (DM), characterised by chronic hyperglycaemia, is a rapidly growing worldwide health problem. The prevalence of DM has been estimated at 3% to 5% of Western populations. The incidence of DM is increasing and will more than double within 15 years, mainly due to adverse lifestyle changes with excess caloric intake and reduced physical activity, which in turn will… View more
Author(s): Douglas Ewan Cannie , Mohammed Majid Akhtar , Perry Elliott Added: 3 years ago
Heart failure is a global health challenge, affecting 1–2% of the population and up to an estimated 64 million people worldwide.1,2 In the UK, just under 1 million people have heart failure, with approximately 350 new diagnoses each year per 100,000 population.3 The lifetime risk of developing heart failure at 55 years of age is 33% for men and 28% for women.4 The heart failure population is… View more
Author(s): Maki Komiyama , Koji Hasegawa , Akira Matsumori Added: 3 years ago
The novel coronavirus disease (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a public health emergency of international concern.1 The pandemic is ongoing, and the world is faced with the urgent task of minimising the mortality associated with COVID-19. Besides advanced age, risk factors for escalation of COVID-19 severity include underlying… View more