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Role of the Thyroid System in the Dynamic Complex Network of Cardioprotection

… 2016;11(1):36-42 DOI: https://doi.org/10.15420/ecr.2016:9:2 Correspondence: Professor Alessandro Pingitore, Clinical … the expression of the peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1 alpha) and the … System and Inflammation Plasma cytokines, in particular interleukin 6 (IL-6) and tumour necrosis alpha (TNF-alpha), …

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Cardiac Resynchronisation Therapy and Cellular Bioenergetics: Effects Beyond Chamber Mechanics

… to View PDF Permissions Views: 25 Likes: 0 Downloads: 2 Abstract Cardiac resynchronisation therapy is a cornerstone … to undergo conformational changes than the adult one (alpha-myosin). 13 In addition to the electron transport … fatty acid oxidation is peroxisome proliferator-activated receptor-alpha (PPAR-alpha), which increases expression of …

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Anti-inflammatory Action of Curcumin and Its Use in the Treatment of Lifestyle-related Diseases

… the inhibition of nuclear factor-kappaB and Toll-like receptor 4-dependent signalling pathways and the activation … 11 July 2019 Citation: European Cardiology Review 2019;14(2):117-22 DOI: https://doi.org/10.15420/ecr.2019.17.2 … such as tumour necrosis factor-alpha (TNF-alpha) and interleukin (IL)-1beta ( Figure 1 ). 4,15 The US Food and …

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The Effect of Statins on the Functionality of CD4+CD25+FOXP3+ Regulatory T-cells in Acute Coronary Syndrome: A Systematic Review and Meta-analysis of Randomised Controlled Trials in Asian Populations

… to View PDF Permissions Views: 45 Likes: 0 Downloads: 2 Abstract Acute coronary syndrome (ACS) is characterised by … T-cells , cluster of differentiation 4 positive , interleukin-2 receptor alpha chain negative , forkhead box P3 positive , …

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The Role of Inflammation in Diabetes: Current Concepts and Future Perspectives

… into two broad pathogenetic categories, type 1 or type 2 diabetes. The role of obesity, adipose tissue, gut … kinase-beta (IKKbeta), which correlates with the post-receptor action of insulin. 15 A landmark study to correlate … reactants including fibrinogen, C-reactive protein, interleukin (IL)-6, plasminogen activator inhibitor-1, sialic …

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Left Ventricular Remodelling: A Problem in Search of Solutions

… to View PDF Permissions Views: 2975 Likes: 0 Downloads: 2 Abstract Cardiac remodelling (REM) is a generally … enzyme inhibitors (ACEI) or angiotensin II receptor blockers (ARBs), betablockers, aldosterone … beta-myosin heavy chain (beta-MHC) and the decrease of alpha-myosin heavy chain (alpha-MHC). The latter is the minor …

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A Selection of Recent Papers as Recommended by the Advisory Panel

… the procedure. Bidirectional Role of Tumor Necrosis Factor-alpha in Coronary Microembolisation: Progressive Contractile … contractile dysfunction. However, TNF-alpha is not only a negative inotrope, but can also protect the myocardium … Mechanisms Linking Obesity to Insulin Resistance and Type 2 Diabetes Kahn SE, Hull RL, Utzschneider KM Nature, …

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Inflammation Revisited: Atherosclerosis in The Post-CANTOS Era

… Study (CANTOS) has provided convincing evidence of interleukin-1 beta as a target whose neutralisation by a … October 2017 Citation: European Cardiology Review 2017;12(2):89-91 DOI: https://doi.org/10.15420/ecr.2017:18:1 … angiotensin-converting enzyme inhibitors and angiotensin receptor blockers, along with the introduction of early …

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Coronavirus Disease 2019 Myocarditis: Insights into Pathophysiology and Management

… a global pandemic of severe acute respiratory coronavirus 2 (SARS-CoV-2). Coronavirus disease 2019 (COVID-19), which is … who are infected with SARS-CoV-2 had high levels of interleukin-1 (IL-1) beta, IL-6, interferon (IFN) gamma, IFN … aminopeptidase that has been identified as a functional receptor for coronaviruses. SARS-CoV-2 infection is triggered …

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Cardiovascular Implications of Sphingomyelin Presence in Biological Membranes

… They are composed of two key lipid building blocks - long-chain bases (usually sphingosine or 1,3-dihydroxy-2-amino-4-octadecene) and fatty acids - and use a … SM levels, erythrocyte membrane SM content and lipoprotein alpha(a) levels were shown. These observations suggest a link …

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