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Association of Vitamin D Deficiency with Acute Myocardial Infarction in Iraqi Patients
Author(s): S Othman Amen , Soza Tharwat Mohammed Baban Added: 3 years ago
Background: Globally, coronary artery disease (CAD) and its complications, such as acute myocardial infarction (AMI), are the leading cause of morbidity and mortality. Vitamin D deficiency is a prevalent condition and it is emerging as a new risk factor for CAD. However, the correlation between vitamin deficiency and an increased risk of developing cardiovascular disease remains elusive. Aim: To… View more

Prevention & Chronic Conditions

MI/ACS
Association of Hyperhomocysteinemia with Acute Myocardial Infarction in Iraqi Patients
Author(s): S Othman Amen , Soza Tharwat Mohammed Baban Added: 3 years ago
Background: Coronary artery disease (CAD) and its major manifestation acute MI (AMI) are the most common causes of death worldwide. Hyperhomocysteinemia (HHcy) has been recently recognised as a new emerging cardiovascular risk factor mediating in development of CAD risk. HHcy causes endothelial dysfunction, resulting in local thrombosis and subsequent ischaemia. However, the role of HHcy in… View more

Prevention & Chronic Conditions

MI/ACS
Author(s): Torbjørn Omland Added: 3 years ago
Acute coronary syndromes (ACS) and heart failure (HF) are both associated with complex neurohormonal activation. Commensurate with advances in pharmacological and device therapies for both conditions, the concept of using circulating biomarkers for diagnosis and risk stratification, as well as for targeting and monitoring therapy, has received great attention. Although many novel biomarkers have… View more

Heart Failure

MI/ACS
Author(s): Christian Müller Added: 3 years ago
B-type natriuretic peptide (BNP) and N-terminal prohormone brain natriuretic peptide (NT-proBNP) have been shown to be extremely helpful in the diagnosis and management of patients with heart failure (HF). These neurohormones are secreted from both the left and the right cardiac ventricle in response to ventricular volume expansion and pressure overload. BNP and NT-proBNP can be seen as… View more

Heart Failure
Assessing Atherosclerotic Cardiovascular Disease Risk with Advanced Lipid Testing: State of the Science
Author(s): Charles Amir German , Michael D Shapiro Added: 3 years ago
Cardiovascular disease (CVD) is the leading cause of mortality in the world, accounting for 17.9 million deaths per year and 31% of deaths worldwide.1 In addition to the toll on human life, the healthcare cost of CVD continues to grow, with estimates of up to US$1.1 trillion by 2035.1 Given the significant public health burden of disease as well as the cost of healthcare, we must shift our focus… View more

Prevention & Chronic Conditions
Author(s): Christian Mueller , Evangelos Giannitsis , James L Januzzi Added: 3 years ago
Improvements in the Early Diagnosis of Acute Myocardial Infarction using a Cardiac Troponin T-high Sensitive Assay In the first talk, Christian Mueller, a Professor at the University Hospital in Basel, discussed the unmet needs of current troponin assays and the improvements made in the early diagnosis of acute myocardial infarction (AMI) using the latest cardiac troponin T-high sensitive (cTnT… View more

MI/ACS
Author(s): Christian Müller Added: 3 years ago
B-type natriuretic peptide (BNP) and N-terminal prohormone brain natriuretic peptide (NT-proBNP) have been shown to be extremely helpful in the diagnosis and management of patients with heart failure (HF). These neurohormones are secreted from both the left and the right cardiac ventricle in response to ventricular volume expansion and pressure overload. BNP and NT-proBNP can be seen as… View more

Heart Failure
Author(s): James L Januzzi Added: 3 years ago
The use of natriuretic peptide testing has dramatically risen recently, in recognition of the value of these blood tests for assisting in the evaluation of patients with suspected heart failure (HF). B-type natriuretic peptide (BNP) is formed as a consequence of production of a 108-amino-acid precursor peptide that is synthesised within the cardiomyocyte; this 'pro-BNP108' is subsequently cleaved… View more

Heart Failure

Prevention & Chronic Conditions
Author(s): PO Collinson Added: 3 years ago
The natriuretic peptides are a family of ring shaped vasoactive hormones showing considerable sequence homology. Four natriuretic peptides have been described, named A-D type (see Figure 1). Of these, commercial immunoassays have been developed for B type natriuretic peptide (BNP) and the N terminus of the prohormone, N terminal pro BNP (NTproBNP). There has been an explosion of clinical studies… View more

Heart Failure

MI/ACS
Author(s): Miriam Reiter , Tobias Reichlin , Raphael Twerenbold , et al Added: 3 years ago
Acute myocardial infarction (AMI) is a major cause of morbidity and mortality worldwide. Accordingly, prompt identification of patients with AMI is critical, as established therapies exist that are of proven benefit.1,2 More than 15 million patients per year present to emergency departments with symptoms compatible with acute myocardial ischaemia in the US and Europe; only 20–30%, however, are… View more

Heart Failure