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Author(s):
Mariëlle GJ Duffels
,
Eric Boersma
,
Barbara JM Mulder
Added:
3 years ago
Congenital heart disease is the most common congenital malformation and accounts for about eight cases per 1,000 births.1 Due to tremendous developments in cardiac surgery, nearly 90% of all children with congenital heart disease reach adult age. In patients with congenital heart disease, pulmonary arterial hypertension (PAH) may develop due to increased pulmonary arterial flow as a result of a…
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Author(s):
Victor F Tapson
Added:
3 years ago
Chronic thromboembolic pulmonary hypertension (CTEPH) results from obstruction of the major pulmonary arteries by unresolved or organized pulmonary emboli that have become incorporated into the vessel wall, ultimately causing increased pulmonary vascular resistances. Without intervention, CTEPH is a progressive, fatal disease for which there is no proven effective medical therapy. Pulmonary…
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Author(s):
Simon G Pearse
,
Martin R Cowie
,
Rakesh Sharma
,
et al
Added:
3 years ago
Despite advances in therapy, heart failure (HF) continues to be a leading cause of hospitalisation in those over 65.1 Around 2 % of people in Europe live with HF and as many as 10 % of those over 75 years are affected.2 Prognosis continues to be poor, with approximately half of patients dying within 5 years of first hospitalisation,3 a more severe prognosis than many malignancies.4
Sleep…
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Author(s):
Mahmoud Abdelnabi
,
Nouran Eshak
,
Yehia Saleh
,
et al
Added:
3 years ago
Pathophysiology of COVID-19-related Cardiac Injury
Acute myocarditis is a potentially life-threatening disease, which is most commonly caused by a viral infection. Among the viruses, the most cited are enteroviruses (especially coxsackievirus), adenovirus and parvovirus B19 and, rarely, coronavirus.
Recently, coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory…
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Author(s):
Leonardo Guimaraes
,
David del Val
,
Sebastien Bergeron
,
et al
Added:
3 years ago
Major advances in heart failure (HF) management have been achieved over the past three decades, yet it remains a syndrome with high morbidity and mortality, poor quality of life and high healthcare costs. Despite all advances in medical/device therapy, many HF patients continue to deteriorate, leading to poor quality of life and high rehospitalisation and mortality rates.1 The recent European…
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Author(s):
Maurice Beghetti
Added:
3 years ago
Congenital heart diseases (CHDs) are among the most common congenital malformations at birth, with an incidence of 8/1,000 live births. These defects are characterised by a heterogeneous group of abnormal communications and connections between the cardiac chambers and vessels with different haemodynamic consequences and, hence, varying need for follow-up and interventions. The most common forms…
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Author(s):
Angela Maas
,
Sabine Oertelt-Prigione
Added:
3 years ago
While 2020 is only halfway through, we have already experienced a historical year in global healthcare with a high societal impact. When the first severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections were reported in China at the end of 2019, few people realised we would all be affected by a global pandemic several months later.
Women are less susceptible than men to many…
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Author(s):
Madelon C Vonk
Added:
3 years ago
Pulmonary arterial hypertension (PAH) is a common and fatal complication of connective tissue diseases (CTDs). By expert consensus, PAH is diagnosed when at right heart catheterisation a mean pulmonary arterial pressure (PAP) >25mmHg at rest or >30mmHg during exercise is measured, together with a normal wedge pressure and a normal or reduced cardiac output.1 The exact pathophysiological…
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Author(s):
Philip Adamson
Added:
3 years ago
A growing appreciation of the prevalence of sleep breathing disorders, especially as co-morbidities of disease syndromes such as chronic heart failure, has increased interest in screening, diagnosis and treatment of obstructive and central sleep apnoea. Sleep apnoea diagnosis currently requires an overnight polysomnograhic evaluation in which the disease is defined as the number of times per hour…
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Transvenous Phrenic Nerve Stimulation - A Novel Therapy for Central Sleep Apnoea in Heart Failure
Author(s):
Sitaramesh Emani
,
William T Abraham
Added:
3 years ago
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