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Author(s): Nazzareno Galiè Added: 3 years ago
The field of pulmonary arterial hypertension (PAH) has recently been characterised by rapid improvements in therapeutic options and corresponding improvements in patient outcomes. In 1991, estimates from the US Department of Health and Human Services National Institutes of Health (NIH) Registry painted a grim portrait of survival in patients with pulmonary hypertension – then called primary… View more
Dr Christopher Cook is a MRC Clinical Research Fellow at the National Heart and Lung Institute, Imperial College London. He studied Medicine at UCL, graduating with Distinction and multiple prizes including the prestigious Proxime Accessit Gold Medal Medicine (London) in 2009. His primary research interests are in the fields of coronary physiology and invasive haemodynamics. He was the winner… View more
Dr Danny Dvir, serves as the Director of Interventional Cardiology at The Shaare Zedek Medical Center in Jerusalem. With a profound dedication to advancing cardiovascular medicine, his research interests span various domains, including Interventional Cardiology, Internal Medicine, Primary Care, Coronary Intervention, Transcatheter Valve Intervention, and Structural Heart Innovations. View more
DrAniket Rali was born in Ahmedabad, Gujarat and moved to the US in 2003. He subsequently earned his double bachelor's degree in Molecular and Cellular Biology and Political Science from Vanderbilt University. He graduated with an MD from the University of Tennessee and completed his residency in Internal Medicine at Case Western University. Dr Rali completed a fellowship in cardiovascular… View more
Author(s): Jean-Luc Vachiéry Added: 3 years ago
Prostacyclins in PAH - Pathobiological Rationale Endothelial dysfunction is the cornerstone event in the pathobiology of pulmonary arterial hypertension (PAH), a rapidly evolving clinical syndrome of dyspnoea and fatigue eventually leading to right ventricular failure and death.1 In the pulmonary vascular bed, endothelial cells are the major source of mediators modulating pulmonary vascular tone… View more
Author(s): Nazzareno Galiè Added: 3 years ago
The field of pulmonary arterial hypertension (PAH) has recently been characterised by rapid improvements in therapeutic options and corresponding improvements in patient outcomes. In 1991, estimates from the US Department of Health and Human Services National Institutes of Health (NIH) Registry painted a grim portrait of survival in patients with pulmonary hypertension - then called primary… View more
Research Area(s) / Expertise: Job title: Professor of Cardiology
Dr Carina Blomström-Lundqvist is Professor of Cardiology at the Department of Cardiology, Institution of Medical Science, Uppsala, SE and Senior Consultant and Professor at the Department of Cardiology and Medical Science, Örebro University Hospital, Örebro, SE. Dr Blomström-Lundqvist graduated in medicine in 1976, she went on to specialise in cardiology and internal medicine, and started… View more
Author(s): Luca Di Chiara Added: 3 years ago
Anaphylaxis is clinically defined as a severe systemic allergic reaction of rapid onset, the hallmarks of which are acute cardiovascular and pulmonary dysfunction. In anaesthetics the incidence of this severe complication is between 1:5,000 and 1:25,000, and it is one of the few remaining causes of mortality directly due to general anaesthesia. During cardiac surgery, children are exposed to… View more
Author(s): Wouter Jacobs , Anton Vonk-Noordegraaf Added: 3 years ago
Abstract Pulmonary arterial hypertension is a progressive disease of the pulmonary vasculature, ultimately leading to right heart failure and death. Current treatment is aimed at targeting three different pathways: the prostacyclin, endothelin and nitric oxide pathways. These therapies improve functional class, increase exercise capacity and improve haemodynamics. In addition, data from a meta… View more