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Effects of Statin Treatment on Patients with Angina and Normal or Nearly Normal Angiograms
Author(s): Olivia Manfrini , Peter Amaduzzi , Maria Bergami , et al Added: 3 years ago
Statins are commonly used in patients with hypercholesterolaemia and in those with cardiovascular diseases – that is, peripheral artery disease and coronary artery disease (CAD) – for the prevention of atheromatous plaque development, progression and complications, with the aim of reducing subsequent major adverse cardiovascular events (MACE), i.e. cardiac death, acute MI, stroke and heart… View more

Prevention & Chronic Conditions
Author(s): Kausik Ray , , , et al Added: 1 year ago
This Radcliffe medical educational programme has been funded by an arm’s length sponsorship by Novartis Pharmaceuticals UK Limited (“Novartis”). Novartis has had no input in development of the content or involvement in the delivery or execution of the educational programme. In this broadcast, we took a detailed look at how the NHS Long-Term Plan will impact the delivery of lipid-lowering… View more

Prevention & Chronic Conditions
Author(s): Antonio J Vallejo-Vaz Added: 3 years ago
Elevated LDL cholesterol (LDL-C) plays a major role in the development of atherosclerotic cardiovascular disease (ASCVD). Multiple studies and meta-analyses, including randomised controlled trials, prospective cohort studies and Mendelian randomisation studies, have consistently shown an association between LDL-C and ASCVD risk that is proportional to the magnitude and duration of exposure to… View more

Prevention & Chronic Conditions
Vera Bittner
Job title: Professor / Section Head, General Cardiology, Prevention and Imaging
Dr Vera Bittner, MD, MSPH, is Professor of Medicine at the University of Alabama at Birmingham and Section Head of General Cardiology, Prevention, and Imaging in the Division of Cardiovascular Disease. Dr Bittner also serves as Medical Director of the Coronary Care Unit and the University Hospital Cardiac Rehabilitation Program. Most of her research has focused on secondary prevention of… View more
Rheumatoid Arthritis and Atherosclerotic Cardiovascular Disease
Author(s): Anne Mirjam Kerola , Silvia Rollefstad , Anne Grete Semb Added: 2 years ago

Prevention & Chronic Conditions
Author(s): Philip A Poole-Wilson Added: 3 years ago
Introduction Coronary heart disease (CHD), due to atheromatous obstruction of coronary arteries, is the most common form of heart disease. The atheroma forms and accumulates in the wall of the coronary artery (coronary atherosclerosis) beginning at an early age. The disease is thought to be initiated by damage to the endothelium - the inner lining of the vessel wall - as a consequence of a… View more

Prevention & Chronic Conditions
Author(s): Christopher Huggins , Nicoletta Charolidi , Gillian W Cockerill Added: 3 years ago
The concentration of plasma low-density lipoprotein cholesterol (LDL-C) is reduced, while that of total high-density lipoprotein cholesterol (HDL-C) is increased, following inhibition of cholesteryl ester transfer protein (CETP). This combined effect has made inhibition of CETP an attractive pharmacological approach for reducing the residual incidence of cardiovascular disease (CVD) remaining… View more

Prevention & Chronic Conditions
Meeting real-world challenges in hypercholesterolaemia management
Author(s): Maciej Banach , Yassir Javaid , Lale Tokgözoğlu , et al Start date: May 12, 2022

Prevention & Chronic Conditions
Author(s): Heather Currie , Christine Williams Added: 3 years ago
Cardiovascular disease (CVD) is the leading cause of death in both men and women, yet the extent of the problem in women is frequently underestimated and, compared with men, women are less likely to be offered interventions, are less likely to be represented in clinical trials and have a worse prognosis. This article aims to examine the extent of the problem of CVD in women, summarise the… View more

Demographic

Prevention & Chronic Conditions
Author(s): Franz H Messerli , Georg Noll , Lars H Lindholm , et al Added: 3 years ago
Recent evidence supports a central role for calcium channel blockers (CCBs), and in particular the dihydropyridine (DHP) agents, in the treatment of hypertension and cardiovascular disease (CVD). We review here the findings of recent trials, systematic reviews and meta-analyses that rebut those of the single, yet widely-publicised, earlier unfavourable meta-analysis. In these latest reports, CCBs… View more

Prevention & Chronic Conditions