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Author(s): Dimitris Tousoulis , Evangelos Oikonomou , Gerasimos Siasos , et al Added: 3 years ago
Diabetes mellitus (DM) is a group of diseases characterised by metabolic disturbances with increasing prevalence worldwide.1 Individuals with DM present several detrimental micro- and macrovascular complications such as retinopathy, nephropathy, neuropathy, atherosclerosis and coronary heart disease.2,3 Accordingly, efforts for early diagnosis and appropriate management are of ultimate importance… View more
Author(s): Niels Voigt , Dobromir Dobrev Added: 3 years ago
Atrial fibrillation (AF) is common and is associated with significant cardiovascular morbidity and mortality, with stroke being the most critical complication.1,2 Drugs presently used for AF therapy have major limitations, including incomplete efficacy and risks of life-threatening proarrhythmic events (antiarrhythmic drugs) and bleeding complications (anticoagulants).3 Non-pharmacological… View more
Author(s): Marco Metra , Savina Nodari , Livio Dei Cas Added: 3 years ago
Beta-blocker therapy remains one of the most fascinating issues in heart failure (HF) clinical practice. These agents, once absolutely contraindicated in patients with HF, have been shown to have the greatest beneficial effects on the patients' prognosis. They have radically changed the clinical course of HF, more than any other agent previously introduced, and are now the cornerstone of current… View more
Author(s): Marco Metra , Savina Nodari , Livio Dei Cas Added: 3 years ago
Beta-blocker therapy remains one of the most fascinating issues in heart failure (HF) clinical practice. These agents, once absolutely contraindicated in patients with HF, have been shown to have the greatest beneficial effects on the patients' prognosis. They have radically changed the clinical course of HF, more than any other agent previously introduced, and are now the cornerstone of current… View more
Author(s): Zenawit Girmatsion , Joachim R Ehrlich Added: 3 years ago
Atrial fibrillation (AF) alters the function of the heart beyond mere changes in cardiac rhythm. It has been associated with untoward clinical outcomes in patients, such as the development of heart failure and stroke. Recent years have brought attention to several aspects of AF-associated alterations termed ‘remodelling’. This article will provide an overview of pertinent aspects of this subject… View more
Author(s): Esha Sachdev , C Noel Bairey Merz , Puja K Mehta Added: 3 years ago
Takotsubo cardiomyopathy (TTC) has gained more recognition since its first description in 1990 by Satoh et al.1,2 The word takotsubo refers to the Japanese octopus trapping pot with a large round base and narrow neck, which is the characteristic shape of the left ventricle (LV) in this syndrome, although other morphologies have since been described.3 TTC is known by many names including stress… View more