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Immune Cell Traits and Aortic Dissection: A Mendelian Randomisation Study
Author(s): Tian-le Li , Mao-long Fu , Li-hong Wang , et al Added: 1 month ago

Electrophysiology & Arrhythmia

Inherited and Congenital Cardiac Conditions
ACC 25: The MyPEAK-1 Study
Author(s): Milind Y Desai Added: 1 month ago
ACC 2025 - First-in-human results from MyPEAK-1 show Tn-201 treatment in adults with Mybpc3-associated hypertropic cardiomyopathy was feasible and safe.Dr Milind Desai (Cleveland Clinic, Ohio, US) joins us onsite at ACC 2025 to discuss phase Ib/2a results from the first-in-human, non-randomized study investigating the safety and early efficacy of Tn-201, an adeno-associated virus serotype 9 gene… View more

Heart Failure
POTS-associated Conditions and Management Strategies
Author(s): Alexis Cutchins , Svetlana Blitshteyn , Rebecca Steinberg Added: 1 year ago
Postural Orthostatic Tachycardia Syndrome (POTS) is a heterogenous disorder that presents with positional tachycardia, amongst many other symptoms. Evidence for treatment options remains limited, and there are a multitude of associated conditions with overlapping symptoms which can make the diagnosis and management of POTS a difficult experience for providers and patients alike.This broadcast… View more

Electrophysiology & Arrhythmia

COVID-19
The FISH&CHIPS Study: Real-world Study Reveals Significant Reduction in All-cause and Cardiovascular Mortality
Author(s): Jonathon A Leipsic Added: 1 year ago
FISH&CHIPS two-year key outcomes associated with availability of FFRCT include:A significant 14% relative reduction in cardiovascular mortality and a significant 8% relative reduction in all-cause mortality.An increase in cath lab efficiency, driven by a 5% relative reduction in invasive cardiac angiography (ICA) and an 8% relative increase in Percutaneous Coronary Intervention (PCI).A 14%… View more

Guidelines & Statements

Imaging & Diagnostics
ACC 25 Late-Breaking Discussion: The API-Cat Study
Author(s): Harriette Van Spall , Isabelle Mahé Added: 1 month ago
ACC 25 - The API-CAT Study shows reduced-dose apixaban is non-inferior to full-dose apixaban for extended anticoagulation in patients with active cancer who have completed 6 months of anticoagulant therapy for venous thromboembolism (VTE).Late-Breaker host, Dr Harriette Van Spall (McMaster University, Hamilton, CA) is joined by Prof Isabelle Mahe (Paris Cite University, Paris, FR) to discuss the… View more

Anticoagulation

Vascular Disease and Surgery
ACC.24: The Embo-Abl Study
Author(s): Kengo Kusano Added: 1 year ago
ACC.24 — We are joined by Dr Kengo Kusano (National Cerebral and Cardiovascular Center, JP) to discuss the findings from the Embo-Abl Study.Embo-Abl is a multicenter prospective randomized study which aims to compare the incidence of periprocedural cerebral embolisms caused by catheter ablation of atrial fibrillation (AF) between cryoballoon and radiofrequency ablation. 230 patients with AF from… View more

Electrophysiology & Arrhythmia
Erratum: Causal Characteristics of Immune Cells
Author(s): Tian-le Li , Mao-long Fu , Li-hong Wang , et al Added: 6 days ago
ESC 24: SHAM-PVI: Sham Study of Pulmonary Vein Isolation in Symptomatic Atrial Fibrillation
Author(s): Rick Veasey Added: 8 months ago
ESC Congress 24 — SHAM-PVI study finds pulmonary vein isolation effective in reducing atrial fibrillation (AF) episodes, improving quality of life.We are joined onsite by Dr Rick Veasey (Eastbourne District General Hospital, Eastbourne, UK) to discuss the findings from a SHAM-PVI, a randomized sham-controlled study of pulmonary vein isolation in symptomatic atrial fibrillation (NCT04272762; East… View more

Electrophysiology & Arrhythmia
THT 24: The ALT FLOW Early Feasibility Study
Author(s): Firas Zahr Added: 1 year ago
THT 24 - We are joined by Dr Firas Zahr (OHSU Knight Cardiovascular Institute Cardiology Clinic, US) to discuss the findings from the ALT FLOW Early Feasibility study (NCT03523416).The ALT FLOW Early Feasibility study aims to assess the initial clinical safety, functionality and effectiveness of a transcatheter atrial shunt system created by Edwards. 75 patients with symptomatic heart failure… View more

Heart Failure

Intervention
HRS 24: The BIO-CONDUCT Study
Author(s): Larry Chinitz Added: 11 months ago
HRS 24 - Dr Larry Chinitz (NYU School of Medicine, US) joins us to discuss the findings of the prospective, multicenter BIO-CONDUCT study, which investigated the safety and efficacy of the BIOTRONIK Solia S pacing lead implanted in the left bundle branch area (LBB) (NCT05251363, Biotronik Inc.). 186 patients with atrioventricular block, bradycardia, left bundle-branch block or cardiomyopathies… View more

Electrophysiology & Arrhythmia