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Author(s):
Daniel Alejandro Lerman
,
Sai Prasad
,
Nasri Alotti
Added:
3 years ago
Progressive thickening of the aortic valve leaflets and narrowing of the aortic annulus leads to increased mechanical stress on the left ventricle and reduces cardiac output, resulting in further complications.1–3 The proportion of the population affected increases as the median age of a country or region rises. Approximately 2–4 % of people aged over 65 will develop calcific aortic stenosis,…
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Author(s):
Maria Teresa Bayo Jimenez
,
Omar Hahad
,
Marin Kuntic
,
et al
Added:
1 year ago
Author(s):
Shu Nakao
,
Kazuki Yanagisawa
,
Tomoe Ueyama
,
et al
Added:
2 years ago
Author(s):
Niels Voigt
,
Dobromir Dobrev
Added:
3 years ago
Atrial fibrillation (AF) is common and is associated with significant cardiovascular morbidity and mortality, with stroke being the most critical complication.1,2 Drugs presently used for AF therapy have major limitations, including incomplete efficacy and risks of life-threatening proarrhythmic events (antiarrhythmic drugs) and bleeding complications (anticoagulants).3 Non-pharmacological…
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Author(s):
Tomoaki Ishida
,
Tomoe Ueyama
,
Ai Baba
,
et al
Added:
2 years ago
Author(s):
Christos-Konstantinos Antoniou
,
Panagiota Manolakou
,
Nikolaos Magkas
,
et al
Added:
3 years ago
Cardiac resynchronisation therapy (CRT) has been a cornerstone in the treatment of select advanced heart failure cases since its introduction to our armamentarium in the early 2000s.1 Indeed, 30–60% of advanced heart failure patients exhibit evidence of dyssynchrony, when defined electrocardiographically or mechanically.2–4 The latter is a consequence of the former. CRT has several unique…
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Author(s):
Alessandro Pingitore
,
Giorgio Iervasi
,
Francesca Forini
Added:
3 years ago
Cardioprotection includes all methods and mechanisms that lead to the reduction in infarct size, and is thus involved in the evolution of post-ischaemic heart failure (HF). This is a growing research issue since ischaemic heart disease is the leading cause of morbidity and mortality worldwide. A key challenge for these studies is the unravelling of cardioprotection complexities such as the…
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Author(s):
Angela Maas
,
Sabine Oertelt-Prigione
Added:
3 years ago
While 2020 is only halfway through, we have already experienced a historical year in global healthcare with a high societal impact. When the first severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections were reported in China at the end of 2019, few people realised we would all be affected by a global pandemic several months later.
Women are less susceptible than men to many…
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Author(s):
Yoichi Sunagawa
,
Masafumi Funamoto
,
Anna Suzuki
,
et al
Added:
3 years ago
Topic: 3. Heart Failure and Cardiomyopathy
Introduction and Objectives
Maladaptive hypertrophy is being recognized as a critical event during the development of heart failure. In a previous study, we demonstrated that a natural compound, curcumin, prevented cardiomyocyte hypertrophy and the development of heart failure in two different model animals.1–4 Recently, we screened a natural…
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