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Author(s): Luc Janssens Added: 3 years ago
Chronic heart disease is the leading cause of death in both men and women in the US, and coronary artery disease (CAD) constitutes the number one cause among them. Acute ST-segment-elevation myocardial infarction (STEMI) usually occurs when a thrombus forms on a ruptured atheromateus plaque and occludes an epicardial coronary artery. Patient survival depends on several factors, the most important… View more
Author(s): Tito Kabir , Adel Aminian , Andrea Zuffi , et al Added: 3 years ago
The benefit of primary percutaneous coronary intervention (PCI) over hospital-based thrombolysis for ST-elevation myocardial infarction (STEMI) has been established beyond reasonable doubt.1 However, thrombolysis remains an effective and widely used therapy for a significant proportion of STEMI patients and is particularly effective within two hours of the onset of symptoms.2 There may also be… View more
Author(s): Pedro L Sánchez , Isaac Pascual Calleja , Héctor Bueno , et al Added: 3 years ago
The results of an electrocardiogram (ECG) on admission guide the next level of decision-making for the patient with chest pain suspected of myocardial ischaemia. If an occlusive thrombus forms, patients may develop an acute ST-segment-elevation myocardial infarction (STEMI), and the primary goal is to consider reperfusion therapy as quickly as possible. The benefit obtained by effective and early… View more
Author(s): Matthias Gotberg Added: 2 years ago
In this short summary interview, Dr Matthias Götberg (Lund University, Lund, SE) discusses the five-year outcomes of a randomized trial of iFR-guided vs FFR-guided PCI (FR-SWEDEHEART). The study, presented at TCT 2021, demonstrated that the 5-year results of iFR-SWEDEHEART showed no difference in outcome at 5-years compared with FFR. Discussion Points: Importance of the study Study design and… View more
Author(s): Harvey D White , Derek P Chew Added: 3 years ago
The cumulative evidence base informing almost every aspect of myocardial infarction acute coronary syndrome (ACS) care is expansive and has been associated with a decline in the rate of mortality. Within the context of current-era clinical trials of ST-segment-elevation myocardial infarction, 30-day mortality rates of 4–5% have now been reported for high-risk individuals,1,2 with similar rates… View more
Author(s): Lucy Blows , Simon Redwood Added: 3 years ago
Transforming a critically narrowed coronary vessel to one that is angiographically smooth and unobstructed is immensely satisfying. However, if the procedure is examined in its component parts, it is surprising that this technique is considered safe with minimal overt clinical complications. Temporary vessel occlusion renders the downstream myocardium ischaemic, while vessel trauma initiates… View more
Author(s): Lucy Blows , Simon Redwood Added: 3 years ago
Transforming a critically narrowed coronary vessel to one that is angiographically smooth and unobstructed is immensely satisfying. However, if the procedure is examined in its component parts, it is surprising that this technique is considered safe with minimal overt clinical complications. Temporary vessel occlusion renders the downstream myocardium ischaemic, while vessel trauma initiates… View more