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Role of Inflammation in Coronary Epicardial and Microvascular Dysfunction
Author(s): Shigeo Godo , Jun Takahashi , Satoshi Yasuda , et al Added: 3 years ago

Prevention & Chronic Conditions
Coronary Microvascular Spasm
Author(s): Shigeo Godo , Jun Takahashi , Takashi Shiroto , et al Added: 1 year ago

Intervention
Author(s): Niels Voigt , Dobromir Dobrev Added: 3 years ago
Atrial fibrillation (AF) is common and is associated with significant cardiovascular morbidity and mortality, with stroke being the most critical complication.1,2 Drugs presently used for AF therapy have major limitations, including incomplete efficacy and risks of life-threatening proarrhythmic events (antiarrhythmic drugs) and bleeding complications (anticoagulants).3 Non-pharmacological… View more

Heart Failure

Electrophysiology & Arrhythmia
Coronary Artery Spasm: The Interplay Between Endothelial Dysfunction and Vascular Smooth Muscle Cell Hyperreactivity
Author(s): Astrid Hubert , Andreas Seitz , Valeria Martínez Pereyra , et al Added: 3 years ago
Coronary artery spasm (CAS) is an established cause for anginal chest pain, the cardinal symptom of myocardial ischaemia, in patients with angiographically unobstructed coronary arteries. Evidence from large clinical studies has revealed that about 50% of patients undergoing diagnostic coronary angiography for suspected coronary artery disease (CAD) had either normal or near normal coronary… View more

Prevention & Chronic Conditions
Author(s): Gaetano Antonio Lanza Added: 3 years ago
Up to 50% of patients who undergo elective coronary angiography for stable chest pain symptoms that are mainly related to exercise and typical enough to suggest the presence of obstructive coronary artery disease (CAD) are found to have normal or near-normal coronary arteries.1 The mechanisms responsible for angina chest pain in these patients are heterogeneous; accordingly, their identification… View more

Prevention & Chronic Conditions
Environmental Risk Factors for Endothelial Dysfunction
Author(s): Maria Teresa Bayo Jimenez , Omar Hahad , Marin Kuntic , et al Added: 1 year ago

Prevention & Chronic Conditions
Pathophysiology and Diagnosis of Coronary Functional Abnormalities
Author(s): Jun Takahashi , Akira Suda , Kensuke Nishimiya , et al Added: 2 years ago

Prevention & Chronic Conditions
Microvascular Angina: Diagnosis and Management
Author(s): Haider Aldiwani , Suzan Mahdai , Ghaith Alhatemi , et al Added: 2 years ago

Intervention
Preclinical Diagnosis and Risk Assessment of Atherosclerosis
Author(s): Giuseppe Gullace , Hassan Khalaf Added: 3 years ago
The endothelium, which was initially considered to be a semipermeable barrier separating lumen from vessel wall, is now recognised as a complex endocrine organ responsible for a variety of physiological processes vital for vascular homeostasis. These include the regulation of vascular tone, luminal diameter and blood flow; haemostasis and thrombolysis; platelet and leucocyte vessel-wall… View more

Prevention & Chronic Conditions

Demographic
Author(s): Ricardo A Perez de la Hoz , Sandra Patricia Swieszkowski , Federico Matias Cintora , et al Added: 3 years ago
The aim of reviewing the neuroendocrine–humoral response in acute coronary syndrome (ACS) is based on the fact that beyond the distinctive thrombotic event that defines acute occlusion of a coronary artery, generically referred to as a plaque accident, it is not an isolated event. It is clear that a series of physiological and physiopathological mechanisms related to stress – before, during and… View more

Prevention & Chronic Conditions

MI/ACS