Search results
Author(s):
Hossein-Ardeschir Ghofrani
,
Ralph Schermuly
,
Norbert Weissmann
,
et al
Added:
3 years ago
Pulmonary arterial hypertension (PAH) has an estimated prevalence of 15–25 cases/million population.1 This chronic, progressive disease is defined by a mean pulmonary arterial pressure >25mmHg in conjunction with normal pulmonary capillary wedge pressure <15mmHg.2 The disease is characterized by increased vascular resistance of the pulmonary microvasculature, ultimately resulting in right…
View more
Direct Oral Anticoagulants Concentration Testing in Clinical Practice for High-Risk Patients with AF
Author(s):
K Pukite
,
I Urtane
,
I Pupkevica
,
et al
Added:
3 years ago
Article
Author(s):
Grace Shu-wen Chang
,
Doreen Su-Yin Tan
Added:
3 years ago
Warfarin is a widely used anticoagulant for the prevention and treatment of thromboembolic disorders. It is well known that there is considerable inter-individual variability in warfarin dose requirements. Furthermore, because warfarin has a narrow therapeutic window, there is a risk of serious sequelae, such as thromboembolism or bleeding, if international normalised ratio (INR) levels fall into…
View more
Author(s):
Antoni Martínez-Rubio
,
Soledad Ascoeta
,
Fadwa Taibi
,
et al
Added:
3 years ago
In the last months of 2019 and the beginning of 2020, a novel disease appeared, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a very contagious virus, which causes coronavirus disease 2019 (COVID-19). The clinical manifestations of this virus in humans vary widely from asymptomatic to severe, with diverse symptomatology and even death. The substantial transmission from…
View more
Author(s):
Paul A Gurbel
,
David Kandzari
Added:
3 years ago
The rare but catastrophic occurrence of stent thrombosis, in particular 'late' stent thrombosis, in association with deployment of drug-eluting stents has focused attention on the adequacy of the current dual anti-platelet regimen of aspirin and clopidogrel. Stent thrombosis is due to multiple factors. These include, specific stent features (delayed healing or polymer hypersensitivity),…
View more
Author(s):
David G Gent
,
Rebecca Dobson
Added:
11 months ago
Author(s):
Ana Pardo Sanz
,
Jose Luis Zamorano
Added:
3 years ago
Search Strategy
An independent literature search was performed on the topic ‘AF in cancer patients’ with the assistance of professional librarians. The search terms included anticoagulation, cancer, cardioncology, vitamin K antagonist, direct oral anticoagulants, bleeding risk and embolic risk. An electronic search was conducted using a minimum of two major databases (Cochrane Registry, MEDLINE)…
View more
Drug–Device Interactions
Author(s):
Etienne Aliot
,
Josep Brugada
Added:
3 years ago
Article
Author(s):
Laurent Bonello
Added:
3 years ago
Clopidogrel is a key antiplatelet agent that inhibits the second step of platelet aggregation through blockade of the P2Y12-adenosine diphosphate (ADP) receptor.1 Its use has enabled percutaneous coronary intervention (PCI) to expand by dramatically reducing thrombotic complications in acute coronary syndromes (ACSs).2,3 Since the first report by Jaremo et al. of a large inter-individual…
View more