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Author(s): Ayumi Katayama , Masafumi Funamoto , Kana Shimizu , et al Added: 3 years ago
Best Abstract Award – Second prize Topic: Heart Failure (Basic), Molecular Cardiology Introduction A major morphogenic change in heart failure is the hypertrophy of individual cardiomyocytes. Suppressing cardiomyocytes hypertrophy enables the prevention and treatment of heart failure. Although many experimental studies and clinical intervention trials have shown the cardioprotective effect of… View more

Heart Failure
The Polyunsaturated Fatty Acids EPA and DHA Prevent Myocardial Infarction-induced Heart Failure by Inhibiting p300-HAT Activity in Rats
Author(s): Yoichi Sunagawa , Ayumi Katayama , Masafumi Funamoto , et al Added: 2 years ago

Heart Failure

MI/ACS
Inflammation and Cardiovascular Disease: The Future
Author(s): Natalie Arnold , Katharina Lechner , Christoph Waldeyer , et al Added: 2 years ago

Prevention & Chronic Conditions
New Perspectives on Atherogenic Dyslipidaemia and Cardiovascular Disease
Author(s): Alberto Lorenzatti , Peter P Toth Added: 3 years ago
We are witnessing an epidemic global increase in the prevalence of obesity and its clinical consequences (e.g. insulin resistance and diabetes). This epidemic has been potentiated and sustained by the widespread adoption of unhealthy lifestyles in broad swathes of the population and is characterised by a sedentary lifestyle and an imbalance between the type and characteristics of nutrition,… View more

Prevention & Chronic Conditions

MI/ACS
Remnant Lipoproteins and ASCVD
Author(s): Mohanad Gabani , Michael D Shapiro , Peter P Toth Added: 6 months ago

Prevention & Chronic Conditions
Author(s): Claudia Agabiti-Rosei , Anna Paini , Massimo Salvetti Added: 3 years ago
Uric acid (UA) represents the final product of purine metabolism, in humans mainly regulated by the xanthine-oxidoreductase enzyme, which converts hyoxantine to xanthine and xanthine to UA. Dietary factors may influence serum UA (SUA), increasing its levels (meat, seafood, fructose, alcohol and sodium) or decreasing them (coffee and ascorbic acid). In addition, high cellular turnover conditions,… View more

Prevention & Chronic Conditions
Author(s): Yurina Sugita , Tetsuro Miyazaki , Kazunori Shimada , et al Added: 3 years ago
Topic: Preventive Medicine Background Delirium frequently occurs in patients admitted to the intensive care unit and is associated with mortality and morbidity. Although several studies reported associations between polyunsaturated fatty acids (PUFAs) and cognitive disorders, the association between PUFAs and delirium in patients with acute cardiovascular disease remains unknown. Methods and… View more

Prevention & Chronic Conditions
Author(s): Raffaele De Caterina Added: 3 years ago
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia1 and increases the risk of stroke and thromboembolism, on average, fivefold.2 Strokes in AF are generally more severe and associated with greater mortality and disability than strokes from other causes.3 Prevention of stroke and thromboembolism is therefore an important part of AF management. Guidelines have, until now,… View more

Anticoagulation

Electrophysiology & Arrhythmia
Author(s): Nagara Tamaki , Yuji Kuge , Keiichiro Yoshinaga Added: 3 years ago
The heart requires a high rate of oxygen uptake to maintain mechanical function in order to provide sufficient energy to balance the requirement of the mechanical function. Oxygen consumption increases in almost direct ratio to the increased workload; when the oxygen supply is inadequate for the demand, reversible or irreversible metabolic changes may occur. Such an imbalance is most often… View more

Imaging & Diagnostics

Heart Failure
ACC.23 Late-Breaker Discussion: The CLEAR-Outcomes Trial
Author(s): Harriette Van Spall , Steven E Nissen Added: 1 year ago
ACC.23/WCC — Late-breaker host, Dr Harriette Van Spall (McMaster University, CA) is joined by principal investigator, Dr Steven Nissen (Cleveland Clinic, Cleveland, OH, US) to have a deep dive into the practice-changing CLEAR-Outcomes trial (NCT02993406).The Phase 3 CLEAR-Outcomes trial was conducted to evaluate the impact of bempedoic acid (ETC-1002) on the occurrence of major cardiovascular… View more

Standards & Guidelines

Prevention & Chronic Conditions