Filters
Close
ADDED DATE
Added date
AUTHOR Please select
TOPICS Please select
WATCH / LISTEN / READ TIME
Author(s): Konstantinos Toutouzas , Antonios Karanasos , Dimitris Tousoulis Added: 3 years ago
Acute coronary syndromes (ACS) comprise a major cause of morbidity and mortality. The almost-exclusive cause of ACS, including unstable angina, acute myocardial infarction (AMI) with or without ST-segment elevation, and sudden cardiac death, is atherothrombosis. Pilot pathological studies have identified the pathophysiological processes implicated in the destabilisation and thrombosis of… View more
Author(s): Gianfranco Sinagra , Michele Moretti , Giancarlo Vitrella , et al Added: 3 years ago
According to the latest position statement of the European Society of Cardiology (ESC), cardiomyopathies (CMP) are defined as “myocardial disorders in which the heart muscle is structurally and functionally abnormal, in the absence of coronary artery disease, hypertension, valvular disease and congenital heart disease sufficient to cause the observed myocardial abnormality”.1 CMP may be… View more
Author(s): Lars Rydén , Linda Mellbin , Klas Malmberg Added: 3 years ago
The worldwide prevalence of diabetes in 2010 is already at epidemic proportions with an estimated 284.6 million adults (aged 20–79 years), representing 6.4% of the global adult population.1 However, more worryingly, the prevalence has increased by 15% since 20072 and projections estimate that 438.4 million adults will have diabetes in 2030, a 54% increase on 2010 figures.1 This drastic rise in… View more
Author(s): Michael G Kirby , Geoffrey Hackett , Sudarshan Ramachandran Added: 3 years ago
Testosterone deficiency (TD) is a well-established and significant medical condition.1,2 It has been defined as a clinical and biochemical syndrome, associated with older age and comorbidities.3 It is characterised by a deficiency in serum androgen levels, with or without reduced genomic sensitivity to androgens.2 The latter relates to the functionality of androgen receptors. For example, if… View more
Author(s): Mahmoud Abdelnabi , Nouran Eshak , Yehia Saleh , et al Added: 3 years ago
Pathophysiology of COVID-19-related Cardiac Injury Acute myocarditis is a potentially life-threatening disease, which is most commonly caused by a viral infection. Among the viruses, the most cited are enteroviruses (especially coxsackievirus), adenovirus and parvovirus B19 and, rarely, coronavirus. Recently, coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory… View more
Author(s): Athanassios Manginas , Dennis V Cokkinos Added: 3 years ago
Coronary artery ectasia (CAE) is a relatively common entity causing inappropriate dilatation of the coronary vasculature. The exact mechanism of its development is unknown, but evidence suggests a combination of genetic predisposition, common risk factors for coronary artery disease (CAD) and abnormal vessel wall metabolism. It frequently co-exists with aneurysms elsewhere, mostly involving the… View more
Author(s): William T Abraham Added: 3 years ago
Hyponatremia is the most common electrolytic abnormality in clinical practice and has a reported incidence of 15–30% in adults.1,2 It is particularly common in heart failure: the Organized Program to Initiate Life Saving Treatment in Patients Hospitalized for Heart Failure (OPTIMIZE-HF) registry recorded that 25.3% of 47,647 heart failure patients had hyponatremia on admission.3 In this registry,… View more