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The Effect of Statins on the Functionality of CD4+CD25+FOXP3+ Regulatory T-cells in Acute Coronary Syndrome: A Systematic Review and Meta-analysis of Randomised Controlled Trials in Asian Populations

… Statins on the Functionality of CD4+CD25+FOXP3+ Regulatory T-cells in Acute Coronary Syndrome: A Systematic Review and … box P3 positive , acute coronary syndrome , statins , cytotoxic T-lymphocyte-associated protein 4 , Disclosure: The authors …

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Article

Ion Channel Remodelling in Atrial Fibrillation

… Na + -Ca 2 + - exchanger. These compensatory changes limit cytotoxic Ca 2+ influx but cause further ERP abbreviation, … Kv4.3 gene transcription via a nuclear factor of activated T-lymphocyte-dependent mechanism 56 because calcineurin …

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Article

Troponin in Non-ischaemic Dilated Cardiomyopathy

… that increased cardiac troponin plasma levels are associated with worse prognosis and that further increases in … C (cTnC), cardiac troponin I (cTnI), cardiac troponin T (cTnT) and tropomyosin (see Figure 1 ). Although troponins … 1996;183:949-58. Crossref | PubMed Larrick JW, Wright SC, Cytotoxic mechanisms of tumor necrosis factor-alpha, FASEB J, …

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Article

TBL1 Suppresses Cardiomyocyte Hypertrophy by Regulating the Interaction Between HDAC3 and GATA4

… therapy , p300 acetylation of GATA4 , transducin beta like protein 1 , GATA4-binding protein , cardiomyocytes , atrial natriuretic peptide , … the present study, we have identified transducin beta like protein 1 (TBL1) as a novel GATA4-binding protein by tandem …

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Article

Cardiac Resynchronisation Therapy and Cellular Bioenergetics: Effects Beyond Chamber Mechanics

… through the equation: With H denoting enthalpy, T absolute temperature and S entropy. DG 0 is the standard … pathway activation, such as that mediated by the protein kinase B/mammalian target of rapamycin. 29 The exact … In addition, increased AMP levels lead to AMP-dependent protein kinase (AMPK) activation, which constitutes a central …

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Article

Cardio-oncology: A Focus on Cardiotoxicity

… . 36 New immunotherapy agents such as ipilimumab (an anti-cytotoxic T-lymphocyte-associated protein 4 monoclonal antibody) and …

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Article

Cholesteryl Ester Transfer Protein Inhibitors – Future Soon to be REVEALed

… & Tables References Article Cholesteryl Ester Transfer Protein Inhibitors - Future Soon to be REVEALed Christopher … diseases. However, the putative instrumental variables associated with alleles and clinical outcome are not always … clinical development of these compounds. References Gordon T, Castelli WP, Hjortland MC, et al. High density lipoprotein …

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Article

Electronic Cigarettes and Cardiovascular Risk: Caution Waiting for Evidence

… studies suggest that electronic cigarettes use might be associated with endothelial dysfunction, impaired platelet … Rep 2018;67:1225-32. Crossref | PubMed Franck C, Budlovsky T, Windle SB, et al. Electronic cigarettes in North America: … KE, Romagna G, Allifranchini E, et al. Comparison of the cytotoxic potential of cigarette smoke and electronic …

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Article

European Cardiology - Volume 7 Issue 4

… in the potential of new cholesteryl ester transfer protein antagonists in clinical practice. …

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Edition