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The Effect of Statins on the Functionality
Author(s): Nilofer Sorathia , Hussein Al-Rubaye , Benham Zal Added: 3 years ago
Statins are most frequently prescribed for the primary prevention of cardiovascular disease due to their lipid-lowering properties. They are known to exert their effect by competitive inhibition of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase. The reduction in the synthesis of cholesterol induces upregulation of LDL receptors in the liver, resulting in increased clearance and… View more

Anticoagulation

Prevention & Chronic Conditions
Author(s): Athanasios Koutsoukis , Argyrios Ntalianis , Evangelos Repasos , et al Added: 3 years ago
Cardio-oncology is an emerging field of cardiology that focuses on cardiovascular diseases in patients with cancer. The classic cardio-oncology paradigm is the prevention, diagnosis and treatment of cardiotoxicity resulting from chemotherapy and/or radiotherapy. Diagnosis and treatment of primary and metastatic cardiac tumours as well as cardiac amyloidosis can be considered ‘less classical’… View more

Standards & Guidelines

Prevention & Chronic Conditions
The Association Between Psoriasis and Cardiovascular Diseases
Author(s): Ahmed Zwain , Mohanad Aldiwani , Hussein Taqi Added: 2 years ago

Prevention & Chronic Conditions
NF-kB in Cardiovascular Disease
Author(s): Akira Matsumori Added: 10 months ago

Vascular Disease and Surgery

Imaging & Diagnostics
Author(s): Niels Voigt , Dobromir Dobrev Added: 3 years ago
Atrial fibrillation (AF) is common and is associated with significant cardiovascular morbidity and mortality, with stroke being the most critical complication.1,2 Drugs presently used for AF therapy have major limitations, including incomplete efficacy and risks of life-threatening proarrhythmic events (antiarrhythmic drugs) and bleeding complications (anticoagulants).3 Non-pharmacological… View more

Heart Failure

Electrophysiology & Arrhythmia
Troponin in Non-ischaemic Dilated Cardiomyopathy
Author(s): Andrea Barison , Luigi Emilio Pastormerlo , Alberto Giannoni Added: 3 years ago
Among the various cardiovascular diseases, non-ischaemic dilated cardiomyopathy (DCM) represents a major cause of morbidity and mortality.1 DCM is characterised by the presence of left ventricular dilatation and systolic dysfunction in the absence of coronary artery disease or abnormal loading conditions (hypertension, valvular disease).2 It originates from several aetiologies and includes… View more

Heart Failure
Electronic Cigarettes and Cardiovascular Risk: Caution Waiting for Evidence
Author(s): Domenico D’Amario , Stefano Migliaro , Josip A Borovac , et al Added: 3 years ago
The ancient rite of smoking dates back thousands of years, and tobacco smoking has been largely ingrained in our civilization since the arrival of Europeans to the Americas in the 16th century. For a long time, cigarette smoking was perceived as a symbol of wealth, glamour and sophistication, whereas nowadays it is largely recognised as the first preventable or modifiable cause of common diseases… View more

Prevention & Chronic Conditions
Author(s): Douglas Ewan Cannie , Mohammed Majid Akhtar , Perry Elliott Added: 3 years ago
Heart failure is a global health challenge, affecting 1–2% of the population and up to an estimated 64 million people worldwide.1,2 In the UK, just under 1 million people have heart failure, with approximately 350 new diagnoses each year per 100,000 population.3 The lifetime risk of developing heart failure at 55 years of age is 33% for men and 28% for women.4 The heart failure population is… View more

Heart Failure
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