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Coronary artery stenting has evolved substantially and the performance (and particularly the deliverability) of coronary stents has improved such that they are now the primary mode of revascularisation for almost all PCIs. The new Svelte™ stent-on-a-wire (SOAW) delivery system represents one of the first substantive innovations in stent delivery systems (SDS) in more than a decade. Using a… View more
Author(s): Roxy Senior Added: 3 years ago
Introduction In the UK there is still an emphasis on coronary anatomy as currently assessed using coronary angiography; however, high-grade coronary lesion may not cause myocardial ischaemia, for example in the presence of extensive collateral vessels. Dynamic imaging to show the physiological effect of any coronary stenosis is therefore an important part of the investigation of patients with… View more

Heart Failure

MI/ACS
Bruce Rollman
Job title: Professor of Medicine, Psychiatry, and Clinical and Translational Science
Dr Bruce L Rollman's research focuses on interventions to improve the quality of care for patients with depression and anxiety who are care for in non-psychiatric settings. Dr Rollman was also Principal Investigator for the Bypassing the Blues Trial that demonstrated the effectiveness and cost-effectiveness of a nurse-led and telephone-delivered collaborative care strategy for treating depression… View more
Author(s): Hans-Peter Brunner-La Rocca , Renu Virmani Added: 3 years ago
Incremental cost-effectiveness of drug-eluting stents compared with a third - generation bare-metal stent in a real-world setting: randomised Basel Stent Kosten Effektivitats Trial (BASKET) Kaiser C, Brunner-La Rocca H P, Buser P T, Bonetti P O, Osswald S, Linka A, Bernheim A, Zutter A, Zellweger M, Grize L, Pfisterer ME; BASKET Investigators Lancet (2005);366(9489): pp. 921-929. No… View more

Intervention
Job title: Professor of Cardiology
Prof Klaus Witte is aProfessor of Cardiology at the RWTH University Hospital Aachen, Aachen, DE and at the Leeds Institute of Cardiovascular & Metabolic Medicine, UK. View more
Personalised Approaches to Improving the Effect of Anti-platelet Agents: Where Do We Stand?
Author(s): Lucas C Godoy , Michael E Farkouh Added: 3 years ago
Clopidogrel is the most widely prescribed P2Y12 inhibitor in the world despite the development of newer and more potent agents.1,2 Clopidogrel is administered as a pro-drug and needs to be metabolised by the cytochrome P450 enzymes (particularly by CYP2C19) in order to have biological activity.3 Patients with loss of function (LOF) variants of the CYP2C19 gene have decreased serum levels of… View more

Anticoagulation

Prevention & Chronic Conditions
ACC 23: RENOVATE-COMPLEX-PCI: IVUS Vs OCT Optimisation in Complex PCI
Author(s): Joo-Yong Hahn Added: 1 year ago
ACC.23/WCC - Principal investigator, Dr Joo-Yong Hahn (Samsung Medical Center, KR) joins us to discuss the findings of the RENOVATE-COMPLEX-PCI late-breaking trial (Samsung Medical Center). The investigators compared clinical outcomes between intravascular imaging guided (IVUS) versus angiography guided (OCT) percutaneous coronary intervention (PCI) in 1639 patients with complex lesions … View more

Imaging & Diagnostics

Intervention
EHRA 2019: Wait‑and‑See vs. Acute Cardioversion in Recent‑Onset AF
Author(s): Harry Crijns , Elton Dudink , Nikki Pluymaekers Added: 5 years ago
Prof Harry Crijns (Maastricht University Medical Center, Maastricht, NL) discusses the 'Wait-and-See versus Acute Cardioversion trial in Recent-Onset AF patients' with his colleagues Dr Elton Dudink and Dr Nikki Pluymaekers who conducted the trial. Filmed on site at EHRA 2019 by Radcliffe Cardiology Questions: 1. What is the rationale for this study? 2. What was the design of the trial? 3… View more

Electrophysiology & Arrhythmia
Author(s): Ronald K Binder , Ahmed A Khattab Added: 3 years ago
The treatment of acute myocardial infarction (AMI) has substantially improved in recent decades. Thrombolysis, the former first-line therapy, which is inexpensive and may be administered without noteworthy delay in primary care or pre-hospital settings, has been replaced by primary percutaneous coronary intervention (PCI) despite the inherent delay of transfering patients to a cardiac… View more

Imaging & Diagnostics

MI/ACS
Research Area(s) / Expertise: Job title: Professor of Cardiology
Derek Chew is a clinical and interventional cardiologist as well as a clinical trialist, and health systems researcher in cardiovascular medicine. He has completed a Masters of Public Health at the Harvard School of Public Health, with formal training in epidemiology, trial design, biostatistics, clinical trials and cost-effectiveness analysis. His PhD thesis explored the factors for improving… View more