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A Rare Cardiac Neoplasm Presenting as a Chest Pain

… 'Zellballen' pattern). Immunohistochemical studies were positive for chromogranin, cluster of differentiation (CD) 57 and synaptophysin. Staining for S-100 …

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Article

AHA 2018: BRIDGE-CV Trial

… Sao Paulo, BR) discusses the BRIDGE-CV prevention cluster randomized trial - Effects of a multicentered …

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Video

Circulating Endothelial Progenitor Cells - Characterisation, Function and Relationship with Cardiovascular Risk Factors

… from fresh blood by density gradient centrifugation, and positive pre-selection of mononuclear cells by antibodies … is expressed on subsets of EPCs and HSCs, but in vitro differentiation of these cells results in the loss of AC133 … EPC colonies - defined as flat cells surrounding a cluster of round cells - are counted by two blinded …

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Article

AHA 2018: The Bridge Stroke trial

… The Bridge Stroke Trail at AHA 2018 - An international cluster randomized quality-improvement trial to increase the …

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Video

David Birnie

… leads the Ottawa region strategic research Innovation Cluster on Atrial Fibrillation. Read more …

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Author

Hypertrophic Cardiomyopathy in Athletes

… ventricular hypertrophy (LVH) in response to exercise. Differentiation of physiological LVH from HCM requires an … studies that help shed further light to aid the clinical differentiation of physiological LVH from HCM. This … reveal any phenotypic features of HCM and in such genotype positive/phenotype negative individuals, the exercise …

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Article

Cardiac Repair and Regeneration: The Value of Cell Therapies

… certain endogenous cardiac stem cells undergo growth and differentiation, regulated either by secreted inflammatory … kinases (ERK) by 5-azacytidine seems to trigger the differentiation of human MSCs into cardiomyocytes in vitro. … cells. Histologically, pericytes are identified as cells positive for CD146 but negative for endothelial markers such …

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Article

Cavin-2 Deficiency Attenuates Cardiac Fibrosis and Dysfunction in Pressure-overloaded Hearts

… matrix (ECM) turnover is involved in poor outcome. Trans-differentiation of fibroblasts into activated myofibroblasts … of cardiac fibrosis and systolic dysfunction with the differentiation of fibroblasts into myofibroblasts. Cavin-2 …

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Article

Bone Marrow Stem Cell Treatment for Myocardial Regeneration

… intra-myocardially and the risk of foreign tissue differentiation following local stroma cell injections. … discussion. The data were interpreted to indicate trans-differentiation of adult hematopoietic stem cell by crossing … before established treatment protocols are available. The positive initial clinical experience with intramyocardial …

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Article

Application of CD271+ Human Bone Marrow-derived Stem Cells for Ischaemic Heart Disease Therapy

… 6 Tissue injury might also be a determinant for stem cell differentiation as well as self-renewal. Neural stem cells, … stem cells in vitro . The resulting cells show comparable differentiation potential to embryonic stem (ES) cells. 13 In … first published by our group enables isolation of the positive cell fraction from the bone marrow aspirate without …

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Article