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Destination Therapy with Left Ventricular Assist Devices in Non-transplant Centres: The Time is Right
Author(s): Antoni Bayés-Genís , Christian Muñoz-Guijosa , Evelyn Santiago-Vacas , et al Added: 3 years ago
“The time is always right to do what is right.” – Martin Luther King Jr (1929–1968) Heart failure (HF) has increased at a fast pace during the 21st century to become the main cause of morbidity and mortality for patients with cardiovascular disorders in developed nations, leading to increasing healthcare costs and declining quality of life. The expected prevalence of HF was ~25 million in 2011,… View more

Vascular Disease and Surgery

Heart Failure
Author(s): PO Collinson Added: 3 years ago
The natriuretic peptides are a family of ring shaped vasoactive hormones showing considerable sequence homology. Four natriuretic peptides have been described, named A-D type (see Figure 1). Of these, commercial immunoassays have been developed for B type natriuretic peptide (BNP) and the N terminus of the prohormone, N terminal pro BNP (NTproBNP). There has been an explosion of clinical studies… View more

Heart Failure

MI/ACS
Women and Diabetes: Preventing Heart Disease in a New Era of Therapies
Author(s): Giuseppe Galati , Pierre Sabouret , Olga Germanova , et al Added: 2 years ago

Demographic

Heart Failure
Author(s): Douglas Ewan Cannie , Mohammed Majid Akhtar , Perry Elliott Added: 3 years ago
Heart failure is a global health challenge, affecting 1–2% of the population and up to an estimated 64 million people worldwide.1,2 In the UK, just under 1 million people have heart failure, with approximately 350 new diagnoses each year per 100,000 population.3 The lifetime risk of developing heart failure at 55 years of age is 33% for men and 28% for women.4 The heart failure population is… View more

Heart Failure
Author(s): Eric Prystowsky , Jean-Yves Le Heuzey Added: 3 years ago
For decades, conventional wisdom suggested that sinus rhythm was preferred over rate control in the treatment of patients with atrial fibrillation (AF). Recent randomised trials have been unable to substantiate this viewpoint, and the occurrence of serious outcomes for patients has been similar for both treatment strategies.1,2 More specifically, several large, randomised, prospective clinical… View more

Heart Failure

Electrophysiology & Arrhythmia
Author(s): Jordi Perez-Rodon , Enrique Galve , Carmen Pérez-Bocanegra , et al Added: 3 years ago
Topic: 3. Heart Failure and Cardiomyopathy Introduction and Objectives Although treatment optimization in patients with heart failure and reduced left ventricular ejection fraction (HFrEF) may result in left ventricular reverse remodelling (LVRR) in some cases, predictors of this phenomenon are scarce. This study aimed to: 1) determine the incidence and predictors of absence of LVRR after… View more

Heart Failure

Electrophysiology & Arrhythmia
Author(s): Daniel Alejandro Lerman , Nasri Alotti , Kiddy Levente Ume , et al Added: 3 years ago
Acute myocardial infarction (AMI) is still a major public health problem worldwide, causing high rates of morbidity and mortality. In the United States, nearly one million patients suffer from AMI each year.1 In the UK, around 80,000 people died from coronary heart disease (CHD) in 2010.2 The current approach to the treatment of myocardial infarction involves early revascularisation with… View more

Vascular Disease and Surgery

Heart Failure
Author(s): Andrew K Roy , John Keaney , Niall G Mahon , et al Added: 3 years ago
The coexistence of heart and kidney disease represents an evolving epidemic in an ageing population, with chronic kidney disease (CKD) incidence rates increasing annually.1 The effect of dysfunction of one kidney mediates profound effects on the other, recently described and defined as five distinctive cardiorenal subtypes by the Acute Dialysis Quality Initiative consensus group.2 Much work has… View more

MI/ACS
Milton Packer
Job title: Distinguished Scholar in Cardiovascular Science
Personal History Dr Milton Packer was born to Polish immigrants in 1951 and raised in Philadelphia, US. Prior to studying medicine, he was politically active in the 1960s. In his words: “The focus of my upbringing was education, but the major guiding principle in my childhood years (and throughout my entire life) was an uncompromising sense of justice. I was always imbued with the need to… View more
Author(s): Krishna Prasad Added: 3 years ago
The field of cardiology has seen an unprecedented level of development in recent years both in terms of new therapeutic agents and devices. The field of cardiovascular therapeutics is fast approaching the state of an 'all inclusive area' with the overlap of areas such as diabetes and lipids. With advent of the recent changes to European pharmaceutical regulations, including the clinical trial… View more

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