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Ramon Varcoe
Research Area(s) / Expertise:

Peripheral Artery Disease - General

 Job title: Associate Professor of Vascular Surgery
Professor Varcoe is a vascular surgeon at Sydney’s Prince of Wales Hospitals where he is director of the operating theatres and of the Vascular Institute, one of Australia’s most prestigious clinical trials centres. His clinical practice specialises in the minimally invasive treatment of aortic conditions, carotid disease and the full gamut of occlusive arterial disease of the lower limb for… View more
Author(s): Daniel Alejandro Lerman , Sai Prasad , Nasri Alotti Added: 3 years ago
Progressive thickening of the aortic valve leaflets and narrowing of the aortic annulus leads to increased mechanical stress on the left ventricle and reduces cardiac output, resulting in further complications.1–3 The proportion of the population affected increases as the median age of a country or region rises. Approximately 2–4 % of people aged over 65 will develop calcific aortic stenosis,… View more

Vascular Disease and Surgery

Intervention
Author(s): Mattia Cattaneo , Alberto Froio , Augusto Gallino Added: 3 years ago
Imaging has played an instrumental role in the diagnostic and prognostic assessment of cardiovascular diseases. Arterial Doppler ultrasound, echocardiography, myocardial perfusion imaging tests and angiography are now part of everyday clinical practice and represent a cornerstone of atherosclerosis management.1 During the past two decades, there has been an expansion of the available imaging… View more

Imaging & Diagnostics
Author(s): Martin H Deininger , Juergen Buttler Added: 3 years ago
The association of electrocardiographic (ECG) abnormalities and intracerebral, particularly aneurysmal, subarachnoid haemorrhage (SAH) is a well-known phenomenon. ECG alterations are observed in 50-100% of patients during the acute stage of SAH.1-3 Frequently, these effects are clinically not important. Some SAH patients, however, have structural cardiac damage with elevation of creatine kinase… View more

Heart Failure
Author(s): Suzanne J Baron , Robert P Giugliano Added: 3 years ago
Coronary artery disease remains the leading cause of death in the US and worldwide. Although the incidence of death due to coronary artery disease has declined over the last several years, the prevalence of coronary artery disease remains high, with the American Heart Association (AHA) estimating that over 81 million Americans suffer from cardiovascular disease and 2,200 people dying every day of… View more

Anticoagulation
Author(s): Ricardo Seabra-Gomes Added: 3 years ago
It took great courage around 30 years ago to tackle stenotic lesions within a diseased coronary artery using the percutaneous approach in an unanaesthetised human being. Since then, unbelievable progress and research have been taking place worldwide in a continuum that never seems to end. Percutaneous coronary intervention (PCI) is, for the responsible interventional cardiologist, not only an… View more

Intervention
Author(s): Franz H Messerli , Georg Noll , Lars H Lindholm , et al Added: 3 years ago
Recent evidence supports a central role for calcium channel blockers (CCBs), and in particular the dihydropyridine (DHP) agents, in the treatment of hypertension and cardiovascular disease (CVD). We review here the findings of recent trials, systematic reviews and meta-analyses that rebut those of the single, yet widely-publicised, earlier unfavourable meta-analysis.1 In these latest reports,… View more

Prevention & Chronic Conditions
Author(s): Lars Rydén , Linda Mellbin , Klas Malmberg Added: 3 years ago
The worldwide prevalence of diabetes in 2010 is already at epidemic proportions with an estimated 284.6 million adults (aged 20–79 years), representing 6.4% of the global adult population.1 However, more worryingly, the prevalence has increased by 15% since 20072 and projections estimate that 438.4 million adults will have diabetes in 2030, a 54% increase on 2010 figures.1 This drastic rise in… View more

Prevention & Chronic Conditions
Author(s): Roland E Schmieder Added: 3 years ago
The primary goal in the treatment of hypertensive patients is to achieve the maximum possible reduction in the long-term total risk of cardiovascular (CV) and renal morbidity and mortality. In addition to the lowering of blood pressure (BP) per se, successful realisation of the primary goal of treatment also requires appropriate consideration of co-morbidities.1–3 Although there is some… View more

Prevention & Chronic Conditions
Arrhythmogenic Cardiomyopathy: A Disease or Merely a Phenotype?
Author(s): Alexandros Protonotarios , Perry Elliott Added: 3 years ago
Until the 20th century, conventional medicine relied almost exclusively on observable characteristics to classify and treat human disease.1 Even in the modern era, physicians define diseases using phenotypic similarities and employ relatively simple algorithms to interpret diagnostic tools and plan treatment. The advent of low-cost genetic sequencing and its introduction into clinical care… View more

Heart Failure