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Author(s): Fernando Alfonso Added: 3 years ago
Scale of the Problem Treatment of patients with in-stent restenosis (ISR) remains a significant clinical problem.1 Bare-metal stents (BMS) continue to be used in a large number of patients undergoing percutaneous coronary interventions (PCIs).1–4 BMS are indicated in patients with high bleeding risks or those who are unable to maintain long-term dual antiplatelet therapy. Economic reasons and… View more
Author(s): Remo Albiero Added: 3 years ago
The cutting balloon (CB)1 is a special balloon catheter with three or four atherotomes (microsurgical blades) bonded longitudinally to its surface, suitable for creating discrete longitudinal incisions in the atherosclerotic target coronary segment during balloon inflation. With the cutting balloon, the increase in the vessel lumen diameter is obtained in a more controlled fashion and with a… View more
Author(s): Jacques Machecourt Added: 3 years ago
Drug-eluting stents (DES) have been recognised as a ‘breakthrough technology’ since 2003 due to their unique capacity to reduce clinical restenosis. The difference in restenosis rates, as assessed by angiography, was so large between DES and bare-metal stents (BMS) in the first trials – 0% versus 26% after six months in the first published trial (RAVEL) with the sirolimus-eluting stent (SES),1… View more
Author(s): Ioannis Iakovou Added: 3 years ago
Stent thrombosis (ST) is the sudden occlusion of a stented coronary artery due to thrombus formation. The clinical consequences of ST are frequently catastrophic – most episodes occur within two weeks of stent implantation – and include death in 20–48% or major myocardial infarction (MI) in 60–70% of cases.1–3 When bare-metal stents (BMS) were first introduced, ST was a common complication… View more
Author(s): Ricardo Seabra-Gomes Added: 3 years ago
It took great courage around 30 years ago to tackle stenotic lesions within a diseased coronary artery using the percutaneous approach in an unanaesthetised human being. Since then, unbelievable progress and research have been taking place worldwide in a continuum that never seems to end. Percutaneous coronary intervention (PCI) is, for the responsible interventional cardiologist, not only an… View more
Author(s): Ashok Seth Added: 3 years ago
“I do not know what I may appear to the world, but to myself I seem to have been only like a boy playing on the sea-shore, diverting myself in now and then finding a smoother pebble or a prettier shell than ordinary, whilst the great ocean of truth lay all undiscovered before me.” Sir Isaac Newton Advances in Percutaneous Coronary Intervention – An Overview Over the last 10 years, the… View more
Author(s): Athanassios Manginas , Dennis V Cokkinos Added: 3 years ago
Coronary artery ectasia (CAE) is a relatively common entity causing inappropriate dilatation of the coronary vasculature. The exact mechanism of its development is unknown, but evidence suggests a combination of genetic predisposition, common risk factors for coronary artery disease (CAD) and abnormal vessel wall metabolism. It frequently co-exists with aneurysms elsewhere, mostly involving the… View more