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Author(s): Patricia Fonseca , Raphael Rosenhek , Vinayak Bapat , et al Added: 3 years ago
Degenerative aortic stenosis (AS) is a chronic progressive valvular disease that affects approximately 1.4 % of individuals over 65 years and 4.6 % of patients older than 75 years in the US.1 While the prognosis of asymptomatic patients with severe AS is generally good, that of symptomatic patients is very poor, with an overall mortality of approximately 80 % at three years once the disease… View more

Vascular Disease and Surgery

Intervention
Author(s): Michael H Picard Added: 3 years ago
Non-invasive imaging of the heart continues to evolve and improve. Cardiovascular ultrasound (echocardiography) continues to play an important role in the diagnosis and assessment of responses to therapy of many cardiac conditions. Even as the clinical applications of newer techniques such as cardiac computed tomography (CT) and cardiac magnetic resonance imaging (CMRI) increase, the role of… View more

Imaging & Diagnostics
Author(s): Patricia Fonseca , Anna F Dominiczak , Stephen Harrap , et al Added: 3 years ago
Abstract Early combination therapy is more effective for hypertension control in high-risk patients than monotherapy, and current guidelines recommend the use of either an angiotensin-converting enzyme inhibitor (ACEI) or angiotensin II receptor blocker (ARB) for first-line therapy in patients younger than 55 years. Recent evidence shows that ACEIs reduce mortality, whereas ARBs show no apparent… View more

Prevention & Chronic Conditions
Valvular Heart Disease in Patients with Chronic Kidney Disease
Author(s): Konstantina Kipourou , Jamie M O’Driscoll , Rajan Sharma Added: 2 years ago

Standards & Guidelines

Imaging & Diagnostics
Job title: The Mount Sinai Hospital
Annapoorna Kini,is an endowed Zena and Michael A Wiener Professor of Medicine, Director of Cardiac Catheterization Laboratory at The Mount Sinai Medical Center, Program Director of Interventional Cardiology Fellowship and Director of Structural Heart Intervention Program. Annapoornais an international leader in the field of percutaneous coronary intervention and heart valve therapy. Annapoorna… View more
Author(s): Martijn WA van Geldorp , Johanna JM Takkenberg , Ad JJC Bogers , et al Added: 3 years ago
Prevalence and Causes Degenerative aortic stenosis is the most common valvular heart disease in developed countries. Degeneration results from an active process over decades in a tricuspid or bicuspid valve, leading from mild sclerosis to calcific stenosis. It is characterised by lipid accumulation, inflammation, calcification and even bone formation, and has many similarities to atherosclerosis… View more

Vascular Disease and Surgery

Prevention & Chronic Conditions
Author(s): Lindsay A Smith , Amit Bhan , Mark J Monaghan Added: 3 years ago
The field of non-coronary cardiac intervention is undergoing rapid expansion, driven by advances in technology and increasing demand for alternative, non-surgical therapies for common structural heart diseases. As a result, the volume, variety and complexity of percutaneous catheter-based procedures being performed in cardiac catheterisation laboratories are increasing. Traditionally, fluoroscopy… View more

Imaging & Diagnostics

Intervention
Author(s): Maxime Teisseire , Jérôme Caudron , Jean-Nicolas Dacher Added: 3 years ago
In patients with severe aortic stenosis (aortic valve area <1cm2 or <0.6cm2/m2) and high surgical risk (haemodynamic instability or significant co-morbidities), surgical aortic valve replacement is often rejected and, unfortunately, balloon valvuloplasty cannot provide a sustained improvement. Percutaneous heart valve (PHV) implantation is an excellent alternative treatment in such cases… View more

Vascular Disease and Surgery

Imaging & Diagnostics
Risk of Complications During Pregnancy in Women with Congenital Aortic Valve Stenosis
Author(s): Els Troost , Werner Budts Added: 3 years ago
The prevalence of heart disease in pregnant women is estimated to be between 0.1 and 4%; although the prevalence has not changed for decades, the relative contribution of different types of heart disease varies according to the study population and the study period. Nowadays, in developed countries the largest group of females with an underlying heart disease consists of women with congenital… View more

Demographic

Prevention & Chronic Conditions
Author(s): Otto Kamp , Gabriel Valocik Added: 3 years ago
Background Echocardiography has evolved into the most predominant diagnostic imaging technique in cardiology. Over the last five decades the diagnostic capability of echocardiography has increased dramatically from M-mode to two-dimensional (2-D) imaging. Recent advances in ultrasound instrumentation and computer technology have led to three-dimensional (3-D) echocardiography, introducing a new… View more

Imaging & Diagnostics

Intervention