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Author(s): Zaki Akhtar , Lisa WM Leung , Christos Kontogiannis , et al Added: 2 years ago

Vascular Disease and Surgery

Heart Failure
Author(s): Dipen Shah Added: 3 years ago
Since the first description of catheter ablation for focally initiated atrial fibrillation and focal atrial fibrillation in 1995, the popularity of this catheter intervention has grown practically exponentially and the ablation strategy underlying the intervention has evolved considerably. From ‘point’ ablation within the pulmonary venous vasculature,1 ablation has progressed through circular… View more

Electrophysiology & Arrhythmia
Management of Atrial Fibrillation Using Immunoglobulin Free Light Chains, Novel Biomarkers of Inflammation
Author(s): Akira Matsumori Added: 1 year ago

Imaging & Diagnostics

Heart Failure
Author(s): Philippe Chevalier Added: 3 years ago
Atrial fibrillation (AF), characterised by rapid and irregular activation of the atrium, is the most common arrhythmia in clinical practice, and 2.3 million people in North American and 4.5 million people in the EU are estimated to have paroxysmal or persistent AF.1 An estimated 0.4–1% of the general population are affected with AF,1 with prevalence increasing to nearly 10% in the octogenarian… View more

Electrophysiology & Arrhythmia
Author(s): Gerald V Naccarelli , Deborah L Wolbrette , Soraya Samii , et al Added: 3 years ago
Currently available antiarrhythmic drugs for the treatment of atrial fibrillation are limited in their efficacy and have potential for adverse effects, including torsade de pointes. With the aging of the population, the incidence of atrial fibrillation will double in frequency over the next 15 years. Thus, more effective and safer antiarrhythmic drugs for the treatment of atrial fibrillation are… View more

Electrophysiology & Arrhythmia
Author(s): Maria Cristina Tavera , Sara Foresti , Riccardo Cappato Added: 3 years ago
Before the advent of surgery only 20% of children with congenital heart disease survived to adult life.1 Great achievements in paediatric cardiology and cardiac surgery over the last few decades resulted in an increased survival of children with congenital heart disease (CHD). Today we are facing the first generation of grown-up congenital heart disease (GUCH) patients and the management of their… View more

Electrophysiology & Arrhythmia

Heterogeneous Populations
Author(s): Tonje A Aksnes , Markus P Schneider , Sverre E Kjeldsen , et al Added: 3 years ago
The renin–angiotensin system (RAS) has an important role in many cardiovascular diseases, such as hypertension, left ventricular hypertrophy, atherosclerosis and heart failure, and lately its relationship with cardiac arrhythmias has also been investigated.1 Atrial fibrillation is the most frequently occurring sustained cardiac arrhythmia and its prevalence doubles with each advancing decade of… View more

Electrophysiology & Arrhythmia

Prevention & Chronic Conditions
Author(s): Eric Prystowsky , Jean-Yves Le Heuzey Added: 3 years ago
For decades, conventional wisdom suggested that sinus rhythm was preferred over rate control in the treatment of patients with atrial fibrillation (AF). Recent randomised trials have been unable to substantiate this viewpoint, and the occurrence of serious outcomes for patients has been similar for both treatment strategies.1,2 More specifically, several large, randomised, prospective clinical… View more

Heart Failure

Electrophysiology & Arrhythmia
Author(s): Lori L McMullan , Gaston Vergara , Nassir F Marrouche Added: 3 years ago
Atrial fibrillation (AF) and heart failure (HF) are two disease conditions that are intimately intertwined, both pathophysiologically and clinically. Currently, over 2.3 million people in North America and 4.5 million in the EU have AF, making it the most common arrhythmia encountered in clinical practice.1,2 It is expected that by 2050 there will be over 10 million people with AF.3 The estimated… View more

Imaging & Diagnostics

Heart Failure
Predictors of Recurrence of AF in Patients After Radiofrequency Ablation
Author(s): Iskren Garvanski , Iana Simova , Lazar Angelkov , et al Added: 3 years ago
AF is the most common sustained arrhythmia in clinical routine, and is associated with cardiovascular and cerebrovascular complications, dementia and mortality.1 Pulmonary vein isolation (PVI) in patients with symptomatic AF has become a well-established treatment option.2,3 High acute success rates are achievable, but durable efficacy of previously successful PVIs for AF still remains a… View more

Electrophysiology & Arrhythmia