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Author(s): Rodrigo Alonso , Leopoldo Perez de Isla , Ovidio Muñiz-Grijalvo , et al Added: 3 years ago
Familial hypercholesterolaemia (FH) is the genetic disorder most commonly associated with elevated LDL cholesterol (LDL-C) levels from birth and with premature atherosclerotic cardiovascular disease (ASCVD).1 It is caused by mutations in genes related to the clearance of LDLs such as LDL receptor (LDLR), apolipoprotein B-100 (APOB) and proprotein convertase subtilisin/kexin type 9 (PCSK9).2 The… View more

Prevention & Chronic Conditions
Circulating Biomarkers in Lower Extremity Artery Disease
Author(s): Louise Ziegler , Ulf Hedin , Anders Gottsäter Added: 2 years ago

Vascular Disease and Surgery
Job title: Professor of Medicine and Pathology
Job title: Professor Cardiology, Haceteppe University, Ankara, Turkey
S. Lale Tokgözoglu is Professor of Cardiology at Hacettepe University, Ankara, Turkey. She is currently the President of the European Atherosclerosis Society and Deputy Editor of the European Heart Journal. She chaired the ‘Atherosclerosis and Vascular Biology Working Group of the European Society of Cardiology’ between 2008 and 2010. Professor Tokgözoglu has served on the Board of the Turkish… View more
The Role of C-reactive Protein in Patient Risk Stratification and Treatment
Author(s): Ramón Arroyo-Espliguero , María Carmen Viana-Llamas , Alberto Silva-Obregón , et al Added: 2 years ago

Prevention & Chronic Conditions
Robert Eckel
Research Area(s) / Expertise: Job title: Professor of Medicine
Dr Robert Eckel is Professor of Medicine in the Division of Endocrinology, Metabolism and Diabetes at the University of Colorado Anschutz Medical Campus, Colorado, US.Dr Eckel has held appointments such as the Charles A. Boettcher II Endowed Chair in atherosclerosis research at the University of Colorado, director of the Lipid Clinic at University of Colorado Hospital, and program director of the… View more
Olivier F Bertrand
Research Area(s) / Expertise:
Olivier F Bertrand is assistant professor in the Department of Medicine at Laval University. His research interests include the use of transradial coronary intervention, the cardio-metabolic aspects of atherosclerosis, the imaging of atherosclerosis and therapies for acute MI. He is the principal investigator of the EASY studies and the VICTORY trial. Dr Bertrand graduated in medicine in 1990… View more
Author(s): Antonio J Vallejo-Vaz Added: 3 years ago
Elevated LDL cholesterol (LDL-C) plays a major role in the development of atherosclerotic cardiovascular disease (ASCVD). Multiple studies and meta-analyses, including randomised controlled trials, prospective cohort studies and Mendelian randomisation studies, have consistently shown an association between LDL-C and ASCVD risk that is proportional to the magnitude and duration of exposure to… View more

Prevention & Chronic Conditions
Author(s): Kensuke Nishimiya , Yasuharu Matsumoto , Hiroaki Shimokawa Added: 3 years ago
Vasa Vasorum The coronary arterial wall generally consists of the tunica intima, tunica media and tunica adventitia. In particular, the coronary adventitia harbours the vasa vasorum (VV),which has a diameter of 50–300 μm and plays an important role as a network of nutrient blood vessels to the arterial wall (Figure 1).1–3 The VV is enhanced in association with arterial wall thickening when the… View more

Imaging & Diagnostics
Iana Simova
Research Area(s) / Expertise:
Iana Simova is Associate Professor of Medicine in National Cardiology Hospital in Sofia, Bulgaria. She graduated medicine in Medical University of Sofia and got her Cardiology and Echocardiography degrees in that university. Dr Simova has performed a postgraduate course in Basic Cardiology in Niguarda Hospital, Milan, Italy and training for noninvasive coronary flow reserve evaluation in… View more