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Author(s):
Haruka Ebi
,
Masafumi Funamoto
,
Yoichi Sunagawa
,
et al
Added:
3 years ago
Young Investigator Award
Topic: 3. Heart Failure and Cardiomyopathy
Introduction and Objectives
Maladaptive hypertrophy is being recognized as a critical event during the development of heart failure. We screened natural compounds purified from fruits library and found that Nobiletin, contained in the peel of Citrus depressa, represses phenylephrine-induced hypertrophic responses in…
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Author(s):
Domenic A Sica
Added:
3 years ago
Introduction
Diabetes mellitus is rapidly increasing in its worldwide prevalence and is currently estimated to affect 7-8% of the US population.1 In 2005, 1.5 million new cases of diabetes were diagnosed in people aged 20 years or older in the US. In the not-so- distant past, type-2 diabetes mellitus was viewed as a seemingly benign condition, at least in the elderly, with little effect on life…
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Author(s):
Patricia Fonseca
,
Anna F Dominiczak
,
Stephen Harrap
,
et al
Added:
3 years ago
Abstract
Early combination therapy is more effective for hypertension control in high-risk patients than monotherapy, and current guidelines recommend the use of either an angiotensin-converting enzyme inhibitor (ACEI) or angiotensin II receptor blocker (ARB) for first-line therapy in patients younger than 55 years. Recent evidence shows that ACEIs reduce mortality, whereas ARBs show no apparent…
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Author(s):
Jonathan Jiunn Liang Yap
,
Derek P Chew
,
Gregg Stone
,
et al
Added:
3 years ago
Author(s):
Roland Asmar
Added:
3 years ago
The greatest burden of cardiovascular disease (CVD) is due to non-fatal morbidity and its consequences; whereas CVD accounts for approximately 17 million deaths each year worldwide, current estimates indicate that CVD associated with asymptomatic disease and target organ damage as a result of undetected cardiovascular risk factors affects 128 million people worldwide.1,2 Moreover, the worldwide…
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Author(s):
Robert J Petrella
Added:
3 years ago
Hypertension is a chronic condition and a leading risk factor for the development of cardiovascular (CV) events, which are a major cause of morbidity and mortality worldwide.1–4 CV events create a significant clinical management and economic burden, and are a major cause of hospitalisation and physician visits.5 The burden associated with CV events may be alleviated by treating hypertension,…
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Author(s):
Allegra Battistoni
,
Massimo Volpe
Added:
3 years ago
Cardiovascular and neoplastic diseases are currently the main causes of mortality and morbidity in developed nations.1 These diseases often coexist in the same individual, worsening general condition, complicating therapeutic management and – from a different perspective – raising the issue of possible shared pathophysiological pathways between cardiovascular disease (CVD) and cancer. Many of the…
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Author(s):
Valentina O Puntmann
,
Anastasia Shchendrygina
,
Carlos Rodriguez Bolanos
,
et al
Added:
5 months ago
Author(s):
David K Ryan
,
Debasish Banerjee
,
Fadi Jouhra
Added:
1 year ago
Smoking and Angiotensin-converting Enzyme Inhibitor/Angiotensin Receptor Blocker Cessation to Limit…
Author(s):
Marco Rossato
,
Angelo Di Vincenzo
Added:
3 years ago
Article