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Author(s): Kazuma Ohyama , Yasuharu Matsumoto , Hiroaki Shimokawa Added: 3 years ago
Coronary Artery Spasm and Adventitial Inflammation Coronary artery spasm plays an important role in the pathogenesis of a wide range of ischaemic heart disease, not only in variant angina, but also in other forms of angina pectoris and myocardial infarction.1,2 Recent studies have demonstrated that coronary spasm is also as frequently noted in European people as in Asian people.3 We have… View more

Imaging & Diagnostics

Prevention & Chronic Conditions
ECO 23: Impact of Obesity on Heart Failure Outcomes
Author(s): Laura Meems Added: 11 months ago
ECO 23 - We are joined by Dr Laura Meems (University Medical Center Groningen, NL) to discuss the impacts of obesity on the outcomes of heart failure.In this interview, Dr Meems outlines the effects of obesity on the progression and management of heart failure and the available treatment options for patients in 2023.Interview Questions:How does obesity impact the progression and management of… View more

Heart Failure

Prevention & Chronic Conditions
β3 Adrenergic Receptors in the Sinoatrial Node for Heart Rate Regulation
Author(s): Shu Nakao , Kazuki Yanagisawa , Tomoe Ueyama , et al Added: 2 years ago

Electrophysiology & Arrhythmia
Role of Inflammation in Coronary Epicardial and Microvascular Dysfunction
Author(s): Shigeo Godo , Jun Takahashi , Satoshi Yasuda , et al Added: 3 years ago

Prevention & Chronic Conditions
The Role of Inflammation in Diabetes: Current Concepts and Future Perspectives
Author(s): Sotirios Tsalamandris , Alexios S Antonopoulos , Evangelos Oikonomou , et al Added: 3 years ago
Diabetes is a multifaceted metabolic disorder affecting the glucose status of the human body. Impaired glucose tolerance and hyperglycaemia are the main clinical and diagnostic features and the result of an absolute or relative insulin deficiency or resistance to its action. Chronic hyperglycaemia associated with diabetes can result in end organ dysfunction and failure which can involve the… View more

Prevention & Chronic Conditions
Author(s): Denise Hilfiker-Kleiner , Gerald S Werner , Gerd Heusch Added: 3 years ago
A Cathepsin D-Cleaved 16kDa Form of Prolactin Mediates Postpartum Cardiomyopathy Hilfiker-Kleiner D, Kaminski K, Podewski E, et al. Cell, 2007;128(3):589–600 Postpartum cardiomyopathy (PPCM) is a disease of unknown aetiology exposing women to high risk of mortality after delivery. This study shows that female mice with a cardiomyocyte-specific deletion of STAT3 develop PPCM. In these mice,… View more

Heart Failure
Author(s): Carmela Nappi , Valeria Gaudieri , Alberto Cuocolo Added: 3 years ago
Evaluating stress-induced myocardial perfusion defects by non-invasive myocardial perfusion imaging (MPI) modalities has taken a leading role in the identification of flow-limiting epicardial coronary artery disease (CAD); it has excellent diagnostic and prognostic value. Non-invasive MPI can be performed using conventional and novel gamma cameras or PET/CT.1 A range of imaging techniques has… View more

Imaging & Diagnostics

Prevention & Chronic Conditions
Curcumin in Lifestyle Diseases
Author(s): Kana Shimizu , Masafumi Funamoto , Yoichi Sunagawa , et al Added: 3 years ago
Inflammation involves an array of processes in response to tissue damage resulting from oxidative stress or other causes and triggers repair, such as subsequent extracellular matrix remodelling and fibrosis.1–3 Chronic inflammation continues for a prolonged period, lasting from several months to several years, and is characterised by tissue invasion by inflammatory macrophages. This induces the… View more

Prevention & Chronic Conditions
Mechanisms of Coronary Artery Spasm
Author(s): Kensuke Nishimiya , Jun Takahashi , Kazuma Oyama , et al Added: 10 months ago

Prevention & Chronic Conditions
Author(s): Sven M Francque Added: 3 years ago
Non-alcoholic fatty liver disease (NAFLD) has become the most prevalent chronic liver disease in western countries.1,2 It is closely associated with obesity, diabetes, dyslipidaemia and the metabolic syndrome, and shares common risk factors and pathophysiological mechanisms with these entities.2,3 NAFLD can be associated with hepatocellular damage and inflammation and is then called non-alcoholic… View more

Prevention & Chronic Conditions